Hyalforte Injection (Sodium Hyaluronate)

Adult administration

Typically, 1 syringe is administered once a week for 3 consecutive weeks in the knee joint or shoulder joint, but the frequency of administration can be adjusted according to symptoms.

This medication should not be used in patients with allergies to its components. It should be used with caution in patients with allergies to other medications, patients with liver dysfunction, and patients with skin diseases or infections at the injection site. Severe allergic reactions, such as shock, may occur after administration, so if symptoms arise, discontinue administration immediately and seek appropriate treatment. Symptoms such as facial or periorbital swelling, rash, urticaria, and itching may occur, so if these symptoms arise, stop taking the medication and seek treatment. The injection site may experience temporary pain, swelling, redness, warmth, and a feeling of pressure. Nausea, vomiting, and fever have also been reported, so caution is advised. When using this medication on joints with severe inflammation, worsening of inflammation may occur, so it is advisable to administer it after the inflammation subsides. It is necessary to stabilize the injection site after administration and take care to prevent the medication from leaking out of the joint. Be sure to maintain a sterile environment during injection, and if symptoms do not improve, limit administration to a maximum of three times before discontinuing. If there is fluid accumulation in the joint, it is advisable to aspirate it before the injection. This medication should not be administered directly into blood vessels or the eye, and a 22-23 gauge needle is appropriate for use. Take care when using disinfectants such as benzalkonium chloride or chlorhexidine, as they may cause the medication to precipitate. Women who are pregnant or may become pregnant should carefully consider the benefits and risks before using this medication. Also, since this medication can be excreted in breast milk, it is preferable to avoid breastfeeding during administration. Safety in children has not been established, so it should only be used cautiously when absolutely necessary. Elderly patients may have reduced body function, so special caution is advised during administration.

Serious side effects

Shock symptoms, urticaria

Mild side effects

• Swelling (facial, eyelid, etc.)
• facial flushing
• rash
• itching
• pain
• swelling
• redness
• warmth
• severe local pressure sensation
• nausea

This medication should be stored in a sealed container to protect it from air and light, and kept in a dark place to avoid direct sunlight. Additionally, it is important to store it at a refrigerated temperature between 2 degrees and 8 degrees Celsius, taking care to prevent freezing.

Appearance

A colorless, transparent, and viscous liquid contained in a glass bottle or plastic container (pre-filled syringe) sealed with rubber stoppers at both ends.

Package unit

2.0 milliliters/tube × 3