Amezole Capsule (Omeprazole)

Adult dose

1. Adults 1) Gastric ulcer: Take 1 capsule (20mg) of omeprazole once daily. Most ulcers heal within 4 weeks, although the healing time may vary from patient to patient. If healing is incomplete after the first 4 weeks of treatment, continue treatment for another 2 weeks. In patients who have not responded to other medicines, 2 capsules (40mg) once daily generally result in healing within 8 weeks, although the healing time may vary from patient to patient. Repeat treatment if recurrence occurs. 2) Short-term treatment of duodenal ulcer: Take 1 capsule (20mg) once daily. Most ulcers heal within 2 weeks, although the healing time may vary from patient to patient. If healing is incomplete after the first 2 weeks of treatment, continue treatment for another 2 weeks. In patients who have not responded to other medicines, 2 capsules (40mg) once daily generally result in healing within 4 weeks, although the healing time may vary from patient to patient. Repeat treatment if recurrence occurs. 3) Treatment of reflux esophagitis and symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): - Reflux esophagitis: Take 1 capsule (20mg) once daily. Most cases heal within 4 weeks, although the healing time may vary from patient to patient. If healing is incomplete after the first 4 weeks of treatment, continue treatment for another 4 weeks. In patients who have not responded to other medicines, 2 capsules (40mg) once daily generally result in healing within 8 weeks, although the healing time may vary from patient to patient. Repeat treatment if recurrence occurs. - Treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): Take 1 capsule (20mg) once daily. Treatment for 2-4 weeks is generally sufficient for healing. 4) Maintenance treatment of severe reflux esophagitis and peptic ulcers that are difficult to treat: Take 1 capsule (20mg) once daily. If recurrence occurs, the dose may be increased to 2 capsules (40mg) once daily. 5) Zollinger-Ellison syndrome: The initial dose is 3 capsules (60mg) once daily. Continue treatment, adjusting the dose as appropriate for the individual. More than 90% of patients respond to doses of 1-6 capsules (20-120mg) daily. If taking 4 capsules (80mg) or more daily, divide the dose into 2 administrations per day. 6) Combination therapy with antibiotics to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: - Dual therapy: Take 1 capsule (20mg) of this medicine with amoxicillin 750-1000mg twice daily for 2 weeks. - Triple therapy: Take 2 capsules (40mg) of this medicine once daily or 1 capsule (20mg) twice daily in combination with the following antibiotics. ① Take clarithromycin 250mg and metronidazole 400mg twice daily for 1 week, or ② Take amoxicillin 1g and clarithromycin 500mg twice daily for 1 week. If the treatment response is insufficient, omeprazole monotherapy may be continued. 7) Treatment of gastric or duodenal ulcers or erosions caused by nonsteroidal anti-inflammatory drugs (NSAIDs): Take 1 capsule (20mg) once daily. Most cases heal within 4 weeks, although the healing time may vary from patient to patient. If healing is incomplete after the first 4 weeks of treatment, continue treatment for another 4 weeks. 8) Maintenance prevention of gastric or duodenal ulcers or erosions and dyspeptic symptoms caused by NSAIDs in patients receiving long-term NSAID treatment with a history of gastric or duodenal lesions: Take 1 capsule (20mg) once daily. 9) Prevention of recurrence of reflux esophagitis: Take 1/2 capsule (10mg) once daily to prevent recurrence of reflux esophagitis. * Swallow this medicine whole with at least half a glass of water. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used by those with allergic reactions to any of its ingredients. Caution is needed when administering it to patients with gastric ulcers that may indicate malignancy, as symptoms may improve but actual diagnosis might be delayed. It should not be used together with certain antiviral drugs or antibiotics. Individuals who cannot digest certain sugars due to genetic reasons should also avoid this medication. Patients with poor liver function or the elderly should use this medication cautiously and may require dose adjustments. Neurological symptoms such as headaches, dizziness, drowsiness, insomnia may occur with this medication. Liver function abnormalities may develop, necessitating regular liver function tests, and if any abnormalities are found, the medication should be discontinued. Gastrointestinal symptoms such as diarrhea, abdominal pain, and vomiting may occur frequently. If skin reactions such as rashes or itching occur, the medication should be discontinued immediately. Rarely, serious allergic reactions or blood disorders, muscle pain, and gynecomastia may occur as side effects. Long-term use may increase the risk of fractures, so it should only be administered for the minimum necessary duration when required. This medication reduces stomach acid and may slightly increase the risk of bacterial infections in the stomach; therefore, if diarrhea persists for a long time, a healthcare provider should be consulted. There may be interaction with certain medications, so patients taking other medications must inform their doctor or pharmacist. Women who are pregnant or may become pregnant should use this medication cautiously, and it is advisable to avoid it during breastfeeding. It is recommended not to use in children as safety has not been established. In case of overdose, symptoms such as vomiting, diarrhea, and headaches may occur, and while serious side effects are rare, immediate medical assistance should be sought. This medication should be kept out of the reach of children, should not be stored in a different container, and the cap should be tightly closed after use.

Headache, drowsiness, dizziness, insomnia, paresthesia, fainting sensation, vertigo, confusion, excitement, aggression, hallucination, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, loose stools, constipation, nausea, vomiting, abdominal pain, abdominal distension, dry mouth, stomatitis, gastrointestinal candidiasis, erythema, rash, urticaria, itching, dermatitis, vesicular rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, arthralgia, muscle weakness, myalgia, gynecomastia, cough, asthenia, lethargy, peripheral edema, increased sweating, blurred vision, visual impairment, taste disorder, breast pain in females, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile associated diarrhea, hypomagnesemia, acute generalized pustular psoriasis, eosinophilia with accompanying systemic symptoms due to drug reactions, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyps, hypocalcemia, hypokalemia

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. The recommended storage temperature is room temperature between 1 and 30 degrees Celsius.

Appearance

A hard capsule with a reddish-brown upper part and a pink lower part, filled with white to grayish-white delayed-release granules.

Package unit

For domestic use - 30 capsules/bottle, For domestic use - 100 capsules/bottle, For export - 30 capsules/box [10 capsules/PTP X 3]