Medication info
Proscitol Tablet (Propiverine Hydrochloride)

Proscitol Tablet (Propiverine Hydrochloride)

Prescription medicationTabletOral
Ingredient · strength
Propiverine Hydrochloride›20mg / 1 tablet
Manufacturer / importer
Alvogen Korea Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200410941 · Notified 2004.05.01 · Insurance code 652601480

Summary

Main use
Relief of symptoms of overactive bladder and urinary frequency and incontinence associated with related conditions (e.g., neurogenic bladder)
Who takes it
Adults
Adult dose
Adults: Administer 20 mg of propiverine hydrochloride orally once daily after a meal. The dose may be adjusted according to symptoms. If the effect is inadequate and there are no safety concerns, 20 mg may be taken up to twice daily.

Ingredients

Manufacturer
Alvogen Korea Co., Ltd.

Efficacy & effects

Relief of symptoms of overactive bladder and urinary frequency and incontinence associated with related conditions (e.g., neurogenic bladder)

  • Frequent urination
  • urinary incontinence
  • neurogenic bladder
  • neurogenic frequency
  • unstable bladder
  • bladder irritative state
  • chronic cystitis
  • chronic prostatitis
  • urgency
  • urge urinary incontinence
View approved original text

This medication is used to improve frequent urination and urinary incontinence caused by bladder dysfunctions such as neurogenic bladder, neurogenic frequency, and unstable bladder. It is also effective for bladder irritative conditions due to chronic cystitis or chronic prostatitis. It helps alleviate symptoms such as urgency, frequent urination, and urge urinary incontinence due to an overactive bladder. This medication is used for various bladder-related diseases and symptoms to improve patients' quality of life.

How to take

Adult dose

Adults: Administer 20 mg of propiverine hydrochloride orally once daily after a meal. The dose may be adjusted according to symptoms. If the effect is inadequate and there are no safety concerns, 20 mg may be taken up to twice daily.

Precautions

This medication should not be used in certain patients. For example, it should not be given to patients with allergies to this medication or its ingredients, those with gastrointestinal obstructions, those with decreased gastrointestinal function, those with urinary retention, patients with glaucoma, severe myasthenia gravis, and patients with severe heart disease. Additionally, caution is required when this medication is used in patients with impaired liver or kidney function, those with Parkinson's disease or cerebrovascular disorders, patients with hyperthyroidism, the elderly, and those with autonomic nervous system issues or cardiovascular diseases. This medication may cause serious side effects such as hallucinations, delirium, severe constipation, abdominal bloating, arrhythmias, thrombocytopenia, renal dysfunction, skin rash, acute glaucoma attacks, liver dysfunction, and muscle pain. If any symptoms arise, the use of this medication should be stopped immediately and medical attention should be sought. During the course of treatment, check for other diseases such as bladder cancer, prostate cancer, and urinary tract infections, and address any urinary obstruction caused by benign prostatic hyperplasia. Moreover, this medication may cause drowsiness, dizziness, and vision disturbances; thus, driving or operating hazardous machinery should be avoided. Care should be taken when this medication is used in conjunction with other anticholinergics or specific antidepressants and psychiatric medications, as side effects may be exacerbated. Women who are pregnant or may become pregnant, as well as nursing mothers, are advised against using this medication. Its safety in children has not been established, so it is preferable to avoid use in pediatric patients. Elderly patients may have weakened liver and kidney function, so it is recommended to start with a low dose and administer it cautiously. In the case of overdose, symptoms such as delirium, agitation, seizures, gait disturbances, paralytic ileus, urinary retention, heart disturbances, and elevated blood pressure may occur, and immediate medical treatment should be sought. This medication should be kept out of the reach of children, and it is advisable to avoid transferring it to another container.

Side effects

  • hallucinations
  • delirium
  • paralytic ileus
  • constipation
  • abdominal distension
  • palpitations
  • extrasystole
  • bradycardia
  • QT prolongation
  • ventricular tachycardia
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  • atrioventricular block
  • thrombocytopenia
  • renal dysfunction
  • urinary retention
  • mucocutaneous syndrome
  • fever
  • erythema
  • pruritus
  • conjunctival injection
  • stomatitis
  • increased intraocular pressure
  • acute glaucoma attack
  • nausea
  • headache
  • visual impairment
  • hepatic dysfunction
  • jaundice
  • myalgia
  • weakness
  • rhabdomyolysis
  • thirst
  • abdominal pain
  • nausea
  • vomiting
  • indigestion
  • diarrhea
  • loss of appetite
  • stomatitis
  • glossitis
  • dysuria
  • post-urination dribbling
  • loss of urinary urgency
  • dizziness
  • headache
  • numbness
  • drowsiness
  • insomnia
  • tremor
  • consciousness disturbance
  • perceptual disturbance
  • transient amnesia
  • Parkinsonism
  • dyskinesia
  • hypotension
  • hypertension
  • chest pain
  • hypersensitivity
  • pruritus
  • rash
  • urticaria
  • control disorder
  • dry eye syndrome
  • elevated AST
  • elevated ALT
  • elevated ALP
  • elevated BUN
  • elevated creatinine
  • leukopenia
  • fatigue
  • malaise
  • edema
  • weakness
  • taste alteration
  • low back pain
  • hoarseness
  • sputum
  • agitation
  • heat due to decreased sweating
  • frailty
  • pharyngitis
  • delirium
  • agitation
  • generalized convulsions
  • gait disturbance
  • speech disturbance
  • mydriasis
  • generalized flushing
  • liver impairment

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. It is also recommended to store it at room temperature between 1 to 30 degrees Celsius. Proper storage will ensure the medication's efficacy is maintained safely.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.