Medication info
Alprazolam Tablet 0.5 mg

Alprazolam Tablet 0.5 mg

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.5mg / 1 tablet
Manufacturer / importer
Korea Pharma Co., Ltd.
Appearance
Orange oval tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200410832 · Approved 2004.08.27 · Insurance code 653001580

Summary

Main use
Relief of symptoms of anxiety (including anxiety accompanied by depression), panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
Determine the dose individually to obtain the maximum benefit. The usual daily doses listed below are suitable for most patients, although higher doses may be required. In such cases, increase the dose slowly to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, use the lowest effective dose for the shortest possible duration and frequently reassess the need to continue treatment. ○ Adults 1. For alprazolam, the initial dose is 0.25-0.5㎎ 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this medicine orally in 3 divided doses. If increasing the dose, increase it slowly up to a maximum of 2.4㎎ per day, administered orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with 0.5㎎ of this medicine and, depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎ divided into 3-4 doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; lower doses may sometimes be required.

Ingredients

Manufacturer
Korea Pharma Co., Ltd.

Efficacy & effects

Relief of symptoms of anxiety (including anxiety accompanied by depression), panic disorder, and psychosomatic disorders

  • Anxiety disorders
  • anxiety symptoms
  • anxiety associated with depression
  • psychosomatic disorders
  • gastric and duodenal ulcers
  • irritable bowel syndrome
  • autonomic dysfunction
  • anxiety
  • tension
  • depression
  • sleep disturbances
  • panic disorders
View approved original text

This medication is used for the treatment of anxiety disorders and short-term relief of anxiety symptoms. It is also effective for anxiety symptoms associated with depression. It helps alleviate anxiety, tension, depression, and sleep disturbances caused by psychosomatic disorders. It is also used for the treatment of panic disorders, assisting patients' overall mental health. It effectively addresses various anxiety-related problems, improving symptoms in patients.

How to take

Adult dose

Determine the dose individually to obtain the maximum benefit. The usual daily doses listed below are suitable for most patients, although higher doses may be required. In such cases, increase the dose slowly to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, use the lowest effective dose for the shortest possible duration and frequently reassess the need to continue treatment. ○ Adults 1. For alprazolam, the initial dose is 0.25-0.5㎎ 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this medicine orally in 3 divided doses. If increasing the dose, increase it slowly up to a maximum of 2.4㎎ per day, administered orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with 0.5㎎ of this medicine and, depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎ divided into 3-4 doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; lower doses may sometimes be required.

Precautions

This medication is a benzodiazepine that acts on the central nervous system and is used for sedation and anxiety relief. Care must be taken when using this medication with other narcotic drugs, as it can lead to severe respiratory depression or coma, and even death. Additionally, this medication carries the risk of abuse and dependence, thus it should only be taken at the proper dosage and duration as directed by a physician. It should not be used in individuals with allergies to this medication or certain conditions, such as acute angle-closure glaucoma, severe myasthenia gravis, and severe liver or kidney dysfunction. Patients with heart disease or respiratory issues, elderly individuals, or those who are sensitive to medications should use this medication with extra caution. Drowsiness or decreased concentration may occur while taking this medication, so it is advisable to avoid driving or operating hazardous machinery. Pregnant or breastfeeding women should consult a physician before taking this medication, as it may affect the fetus or newborn. Drug interactions can occur when taken with other medications, leading to enhanced effects or increased side effects, so it is essential to inform the physician of all medications being taken. Sudden discontinuation of this medication can lead to withdrawal symptoms; therefore, doses should be gradually reduced when stopping the medication. In cases of overdose, severe drowsiness, movement disorders, coma, or respiratory depression may occur, and immediate contact with medical facilities should be made. Lastly, special attention is necessary when prescribing to children or the elderly, and the medication should be kept in a safe place out of the reach of children.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle spasms
  • vomiting
  • sweating
  • trembling
  • convulsions
  • seizures
  • excitement
  • increased muscle rigidity
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  • sleep disorders
  • hallucinations
  • anxiety
  • anger
  • irritability
  • aggressive behavior
  • hostile behavior
  • hyperreactivity
  • hostility
  • obsessive thoughts
  • drowsiness
  • ataxia
  • memory impairment
  • dysphonia
  • dizziness
  • headaches
  • balance disorders
  • coordination disorders
  • attention disorders
  • hypersomnia
  • somnolence
  • trembling
  • amnesia
  • autonomic nervous system imbalance
  • muscle tone abnormality
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • hepatitis
  • liver dysfunction
  • jaundice
  • dermatitis
  • vascular edema
  • phototoxic reaction
  • muscle weakness
  • urinary incontinence
  • urinary retention
  • sexual dysfunction
  • menstrual irregularities
  • fatigue
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • increased intraocular pressure
  • drowsiness
  • mild headache
  • depression
  • confusion
  • insomnia
  • neuroirritability
  • syncope
  • dizziness
  • inability to sit still
  • thirst
  • diarrhea
  • increased salivation
  • tachycardia
  • palpitations
  • hypotension
  • excitement
  • trembling
  • dermatitis
  • allergy
  • nasal congestion
  • weight gain
  • weight loss
  • fatigue
  • motor coordination disorders
  • hyperreactivity
  • memory damage
  • cognitive impairment
  • abnormal involuntary movements
  • decreased libido
  • confusion state
  • muscle single contractions
  • increased libido
  • libido changes
  • weakness
  • abnormal muscle tone
  • syncope
  • inability to sit still
  • anxiety
  • disinhibition
  • paresthesia
  • polyuria
  • vasomotor disorders
  • unreality
  • abnormal dreams
  • fear
  • warm sensation
  • decreased salivation
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory infection
  • tinnitus
  • muscle cramps
  • muscle rigidity
  • sweating
  • rash
  • increased appetite
  • decreased appetite
  • urination disorders
  • menstrual disorders
  • erectile dysfunction
  • edema
  • urinary incontinence
  • infection
  • seizures
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • elevated liver enzymes
  • jaundice
  • delirium
  • apathy
  • hyperkinesia
  • dyspepsia
  • asthenia
  • chest pain
  • lethargy
  • falls
  • ataxia
  • balance impairment
  • difficulty concentrating
  • hypersomnia
  • somnolence
  • muscle weakness
  • elevated liver enzymes
  • Stevens-Johnson syndrome
  • gynecomastia
  • excessive milk production

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a light-protective container. Additionally, it should be kept at room temperature between 1°C and 30°C. This helps maintain the effectiveness of the drug and prevents degradation.

Appearance and packaging

Appearance

Orange oval tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.