Medication info
Famotidine Tablet (Famotidine)

Famotidine Tablet (Famotidine)

Prescription medicationTablet경구
Ingredient · strength
Famotidine›20mg / 1 tablet
Manufacturer / importer
(주)킵스바이오파마
Appearance
White round film-coated tablets
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 200404863 · Notified 2004.11.15 · Insurance code 693200130

Summary

Main use
Improvement of gastric ulcers, upper gastrointestinal bleeding, gastric mucosal lesions
Who takes it
Adults
Adult dose
1. Gastric, duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, Zollinger-Ellison syndrome: Administer 20 mg of famotidine orally twice daily (after breakfast, after dinner, or at bedtime) or administer 40 mg once daily (at bedtime). In cases of upper gastrointestinal bleeding, treatment typically begins with an injectable form, and oral administration is changed once oral intake is possible. 2. Improvement of gastric mucosal lesions (erosion, bleeding, redness, swelling): Acute gastritis, acute exacerbations of chronic gastritis For adults: Administer 10 mg of famotidine orally twice daily (after breakfast, after dinner, or at bedtime) or administer 20 mg once daily (at bedtime). Dosages should be adjusted according to age and symptoms.

Ingredients

Manufacturer
(주)킵스바이오파마

Efficacy & effects

Improvement of gastric ulcers, upper gastrointestinal bleeding, gastric mucosal lesions

  • Gastric ulcers
  • duodenal ulcers
  • anastomotic ulcers
  • upper gastrointestinal bleeding
  • acute stress ulcers
  • hemorrhagic gastritis
  • gastroesophageal reflux disease
  • Zollinger-Ellison syndrome
  • gastric mucosal erosion
  • gastric mucosal bleeding
  • gastric mucosal redness
  • gastric mucosal swelling
View approved original text

This medication is used for a variety of gastrointestinal disorders, such as gastric and duodenal ulcers, anastomotic ulcers, and upper gastrointestinal bleeding. It is also effective for the treatment of gastroesophageal reflux disease and Zollinger-Ellison syndrome. It improves symptoms such as erosion, bleeding, redness, and swelling of the gastric mucosa that occur during the acute exacerbation of acute and chronic gastritis, helping to maintain the patient's gastrointestinal health. This drug rapidly recovers complex gastric mucosal damage and plays a significant role in preventing bleeding. Therefore, it is actively used for the treatment and alleviation of various gastric-related diseases.

How to take

Adult dose

1. Gastric, duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, Zollinger-Ellison syndrome: Administer 20 mg of famotidine orally twice daily (after breakfast, after dinner, or at bedtime) or administer 40 mg once daily (at bedtime). In cases of upper gastrointestinal bleeding, treatment typically begins with an injectable form, and oral administration is changed once oral intake is possible. 2. Improvement of gastric mucosal lesions (erosion, bleeding, redness, swelling): Acute gastritis, acute exacerbations of chronic gastritis For adults: Administer 10 mg of famotidine orally twice daily (after breakfast, after dinner, or at bedtime) or administer 20 mg once daily (at bedtime). Dosages should be adjusted according to age and symptoms.

Precautions

This drug should not be used in certain patients. It can be dangerous for patients who have a history of allergy to the ingredients contained in this drug or similar medications. Additionally, it contains lactose and should not be used in patients with a genetic disorder that impairs lactose digestion. Caution is also required for some patients when using this drug. Patients with a history of allergies, impaired kidney function, heart disease, poor liver function, and the elderly should use this medication cautiously. In particular, patients with impaired kidney function may have elevated drug concentrations, so dosages may need to be reduced or intervals between doses extended. This drug can cause several serious side effects. Rarely, symptoms such as shock or severe allergic reactions may occur, so symptoms should be closely monitored, and if any abnormalities arise, administration should be stopped immediately, and treatment should be pursued. Regular blood tests are necessary due to the risk of a decrease in blood cell counts or problems such as anemia or thrombocytopenia. There are also risks of severe skin rashes or mucosal damage, liver dysfunction, muscle damage, heart rhythm abnormalities, consciousness disturbances, seizures, nephritis, and pneumonia. If these symptoms occur, drug use should be stopped immediately, and appropriate treatment should be sought. This medication dissolves in the mouth but is not absorbed in the mouth, so it must be swallowed with water or saliva. Patients receiving blood dialysis should be cautious when using this drug in conjunction with other medications, as its effectiveness may decrease. When used with other medications, drug interactions may occur. In particular, the effectiveness of this drug or other drugs may be reduced when used with certain antifungal agents or specific anticancer drugs, so consulting a doctor or pharmacist is necessary. Elderly patients are more likely to have reduced kidney function, which may lead to elevated drug concentrations; thus, dosage adjustments may be necessary. Pregnant women or those who may become pregnant should only use this drug when the benefits of treatment outweigh the risks, and breastfeeding mothers should discontinue breastfeeding as the drug may be transmitted through breast milk. The safety of this drug in children has not been sufficiently confirmed, so it should be used cautiously in children. Lastly, this drug may mask symptoms of gastric cancer, making it important to confirm the presence of malignancy before using it.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, shock, hypersensitivity (anaphylaxis, respiratory distress, generalized flushing, angioedema, facial edema, pharyngeal edema), Stevens-Johnson syndrome, Lyell syndrome, liver dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia, ventricular fibrillation, consciousness disturbances, seizures, interstitial nephritis, acute kidney failure, interstitial pneumonia, contraction failure

Mild side effects

  • Constipation
  • diarrhea
  • dark stools
  • dry mouth
  • nausea
  • vomiting
  • abdominal bloating
  • loss of appetite
  • stomatitis
  • leukopenia
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  • eosinophilia
  • elevated blood pressure
  • flushing
  • tinnitus
  • bradycardia
  • tachycardia
  • atrioventricular block
  • bronchospasm
  • elevated AST (GOT)
  • ALT (GTP)
  • ALP
  • elevated total bilirubin
  • LDH
  • generalized malaise
  • lethargy
  • headache
  • drowsiness
  • insomnia
  • hallucinations
  • anxiety
  • agitation
  • decreased libido
  • abnormal sensations
  • dizziness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is best to maintain storage temperatures between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.