Medication info
Genewon Doxazosin Mesylate Tablet 2 mg

Genewon Doxazosin Mesylate Tablet 2 mg

Prescription medicationTablet
Ingredient · strength
Doxazosin Mesylate›2.43mg / 1 tablet
Manufacturer / importer
Genewon Science Co., Ltd.
Appearance
White rectangular tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200404719 · Notified 2004.06.26

Summary

Main use
Treatment of hypertension and urinary retention and voiding difficulties caused by benign prostatic hyperplasia
Who uses it
Adults
Adult dosage
1. Hypertension: Administer doxazosin mesylate orally at an initial dose of 1㎎ once daily. Depending on the patient's response, increase the dose to 2㎎ after 1 week. To achieve the desired blood pressure control, the dose may be increased slowly at intervals of 1-2 weeks to 4㎎, 8㎎, and 16㎎ per day. If blood pressure is not adequately controlled with this drug alone, it may be administered concomitantly with a thiazide diuretic or β-blocker. 2. Urinary retention and voiding disorders due to benign prostatic hyperplasia: The initial dose is 1㎎ once daily. Depending on the patient's blood pressure, the daily dose may be increased to 2㎎ at intervals of 1-2 weeks, and then gradually increased to 4㎎ and 8㎎. ㆍAdjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Genewon Science Co., Ltd.

Efficacy & effects

Treatment of hypertension and urinary retention and voiding difficulties caused by benign prostatic hyperplasia

  • Hypertension
  • urinary obstruction
  • urinary disorders
View approved original text

This medication is used to control hypertension by stabilizing blood pressure and to alleviate urinary disorders and urinary obstruction symptoms caused by benign prostatic hyperplasia.

Dosage and Administration

Adult dosage

1. Hypertension: Administer doxazosin mesylate orally at an initial dose of 1㎎ once daily. Depending on the patient's response, increase the dose to 2㎎ after 1 week. To achieve the desired blood pressure control, the dose may be increased slowly at intervals of 1-2 weeks to 4㎎, 8㎎, and 16㎎ per day. If blood pressure is not adequately controlled with this drug alone, it may be administered concomitantly with a thiazide diuretic or β-blocker. 2. Urinary retention and voiding disorders due to benign prostatic hyperplasia: The initial dose is 1㎎ once daily. Depending on the patient's blood pressure, the daily dose may be increased to 2㎎ at intervals of 1-2 weeks, and then gradually increased to 4㎎ and 8㎎. ㆍAdjust the dose as appropriate according to age and symptoms.

Precautions

This medication may cause orthostatic hypotension, so start at a low dose and slowly increase the dosage when taking it for the first time. Symptoms such as dizziness or fainting may occur at the beginning of treatment, so caution is necessary. This medication may cause a prolonged erection, which could lead to erectile dysfunction if left untreated, so immediate treatment should be sought at the first signs. This medication should not be used in patients with specific allergic reactions, leukopenia, or hypotension, and in children under 12 years old. Patients with liver function issues should use this medication with caution and monitor for adverse reactions through blood tests while on treatment. Variety of side effects such as dizziness, headache, drowsiness, nausea, constipation, hypotension, and heart-related symptoms may occur during treatment; if symptoms are severe, consult a doctor immediately. When taking this medication, always rise slowly to avoid sudden hypotension, and if hypotension symptoms occur, it is recommended to lower the head and rest. Additionally, avoid driving or operating dangerous machinery until symptoms stabilize. When used in combination with other antihypertensives, diuretics, or certain erectile dysfunction treatments, there may be an increased risk of hypotension, so it is essential to consult a doctor. Women who are pregnant or may become pregnant should consult a doctor before taking this medication, and nursing mothers should avoid administration or discontinue breastfeeding. Children and elderly individuals should use this medication carefully under a doctor's direction, as safety has not been sufficiently established and the risk of side effects is higher. In case of overdose, severe hypotension may occur, so seek immediate medical attention, and this medication cannot be removed by dialysis, requiring professional treatment. Finally, this medication should be kept out of reach of children and should not be transferred to another container for safety.

Side effects

  • Agranulocytosis
  • leukopenia
  • neutropenia
  • thrombocytopenia
  • syncope
  • dizziness
  • headache
  • drowsiness
  • anxiety
  • insomnia
Show 66 more
  • thirst
  • fatigue
  • seizures
  • heaviness in the head
  • sensations of numbness
  • malaise
  • weakness
  • loss of consciousness
  • visual disturbances
  • tinnitus
  • olfactory disorder
  • pain
  • nausea
  • vomiting
  • diarrhea
  • constipation
  • dyspepsia
  • abdominal bloating
  • discomfort in the stomach
  • anorexia
  • dry mouth
  • orthostatic hypotension
  • hypotension
  • palpitations
  • arrhythmia
  • tachycardia
  • peripheral vascular ischemia
  • edema
  • chest tightness
  • angina
  • myocardial infarction
  • cerebrovascular disorder
  • dyspnea
  • rhinitis
  • epistaxis
  • polyuria
  • frequency of urination
  • urinary incontinence
  • erectile dysfunction
  • low back pain
  • urinary tract infection
  • priapism
  • chest pain
  • arthralgia
  • myalgia
  • elevated AST
  • elevated ALT
  • elevated ALP
  • elevated LDH
  • sweating
  • rash
  • itching
  • nasal congestion
  • facial flushing
  • sensory decline
  • gynecomastia
  • allergic reaction
  • bradycardia
  • hepatitis
  • cholestatic hepatitis
  • worsening of bronchospasm
  • urticaria
  • hematuria
  • dysuria
  • nocturia
  • intraoperative iris dilatation syndrome

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture. The recommended storage temperature is room temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

White rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.