Levosil Tablet (Levostipride)

Adult dose

Adults: Administer 25 mg orally 3 times daily before meals as levosulpiride.

This medication should not be used by women who are pregnant or may become pregnant and by nursing mothers. Do not administer this medication to patients with gastrointestinal bleeding, mechanical obstruction, or perforation, as it may be harmful by stimulating gastrointestinal motility. This medication should not be used in patients with specific tumors such as pheochromocytoma, as it may exacerbate hypertension. Administration is contraindicated in patients with allergic reactions or intolerances to this medication. This medication is also inappropriate for patients with liver disease or in the manic phase of bipolar disorder. Caution is needed for patients with malignant lesions in the breast, as this medication may cause breast-related side effects. This medication contains lactose and should not be used in patients with lactose intolerance or related genetic disorders. Careful administration is needed for patients with hypertension, children, and the elderly, particularly avoiding overdose in children. This medication can cause side effects such as amenorrhea, hyperprolactinemia, and gynecomastia due to hormonal secretion abnormalities; if abnormal symptoms appear, it should be discontinued immediately. Rarely, neurological side effects such as tremors, abnormal tongue movements, and restlessness may occur, and dosing should be stopped if these symptoms arise. Long-term use may lead to involuntary movements around the mouth and such symptoms can persist even after discontinuation. Gastrointestinal side effects may include dry mouth, heartburn, nausea, vomiting, diarrhea, and constipation. Cardiac-related side effects such as hypertension or arrhythmias may occur, so caution is needed. Severe neuroleptic malignant syndrome may develop, and if symptoms such as high fever, muscle rigidity, or changes in consciousness appear, the medication should be stopped immediately and treated. Skin rashes or swelling may appear rarely and dosing should be stopped in such cases. It is advisable to avoid activities requiring attention, such as driving or operating machinery, while taking this medication. There may be interactions with other medications, especially when used with anticholinergics, narcotic analgesics, digitalis preparations, and other neuroleptics, so caution is required. Do not take it with alcohol, and if used with medications that pose a risk of cardiac arrhythmia, the cardiac condition should be closely monitored. Avoid using with medications that cause electrolyte imbalance. For pregnant and nursing women, it is safest not to use as safety for the fetus and newborn has not been established. Elderly patients may experience increased drug concentration due to decreased renal function, so dosage adjustment and monitoring for side effects are necessary. This medication can suppress vomiting symptoms, so it should be used cautiously while closely observing conditions causing vomiting. Animal studies have reported that this medication may affect reproductive function and increase the incidence of pituitary and mammary tumors with long-term high-dose administration.

• Amenorrhea
• galactorrhea
• gynecomastia
• tremors
• tongue twisting
• anxiety
• involuntary movements around the mouth
• thirst
• heartburn
• nausea

Store this medication in a tightly closed container to prevent air or moisture from entering. It is best to maintain storage temperatures between 1 and 30 degrees Celsius.

Appearance

White round tablet

Package unit

30 tablets/bottle, 500 tablets/bottle