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Diacerein 50mg
Hard capsule · Prescription medication
Daehwa Pharmaceutical Co., Ltd.

MFDS item code 200404255 · Notified 2004.12.21 · Insurance code 645601270
Treatment of osteoarthritis of the hip and knee
Osteoarthritis is a degenerative disease mainly affecting the hip or knee joints, causing pain and restricted movement in the joints. This disease occurs as the cartilage in the joint gradually wears away, potentially leading to discomfort in daily life. Treatment focuses on pain relief and improving joint function. Therefore, this medication is used to relieve joint pain and inflammation caused by osteoarthritis.
Adults: Administer diacerein 50∼100mg daily orally in 1∼2 divided doses after meals. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.
This medication should not be used by patients with certain diseases. Individuals with inflammatory bowel disease, bowel obstruction syndrome, or unexplained abdominal pain should not take this medication. Additionally, it should be avoided by those allergic to this drug, its components, or related medications. Patients with liver disease or previous liver problems, as well as children under 15 years of age, should also refrain from taking this medication. Since this drug contains lactose, it should not be administered to patients with lactose intolerance or related genetic disorders. This medication should be used cautiously in patients with a history of small intestine or colon diseases, pregnant or nursing women, and elderly individuals over 65 years of age. In particular, elderly patients may require a reduced dosage. Taking this medication may lead to gastrointestinal symptoms such as diarrhea, loose stools, or abdominal pain. Long-term use can lead to severe issues like gastrointestinal bleeding, ulcers, or perforation, so caution is needed. If diarrhea worsens, dehydration or electrolyte imbalances may occur; thus, immediate discontinuation and consultation with a physician are advised. Allergic reactions such as itching, rash, or eczema may occur, and elevated liver enzyme levels may be detected through blood tests due to liver dysfunction. If using for an extended period, it is essential to follow a physician's instructions, and if diarrhea occurs, stop taking the medication and seek guidance from a specialist. There is a risk of liver damage, so if any signs of liver dysfunction appear, discontinue use immediately, and it is advisable to limit alcohol intake. This medication may interfere with the absorption of antacids containing calcium, magnesium, or aluminum; therefore, it should be taken at least 2 hours apart. Furthermore, if taken concurrently with diuretics, it may enhance diuretic effects, leading to dehydration or hypokalemia. Caution is needed when taken with cardiac glycosides, as it may increase the risk of arrhythmias, and supervision by a healthcare professional is recommended. Pregnant or nursing women should preferably avoid this medication. Animal studies have reported delays in fetal bone formation, and the medication may be transmitted through breast milk in small amounts. In the case of an overdose, severe diarrhea may occur, and appropriate treatment such as electrolyte supplementation may be necessary.
Diarrhea, loose stools, abdominal pain, gastrointestinal disturbances (hemorrhage, ulcers, and perforation), pigmentation of the rectal mucosa, itching, rash, eczema, elevated serum liver enzymes
Not everyone experiences these, and they can vary from person to person.
This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature to ensure the longevity of its effectiveness and safety.
A hard capsule with an upper orange and lower light yellow color, containing a brownish powder.
Domestic use - 30 capsules/bottle, Domestic use - 300 capsules/bottle, Export 1 - 30 capsules/bottle, Export 1 - 300 capsules/bottle, Export 2 - 10 capsules/PTP, Export 2 - 20 capsules/box [10 capsules/PTP*2], Export 2 - 100 capsules/box [10 capsules/PTP*10]
Even with the same ingredient, strength, dosage form and how it is taken can differ.
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Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.