Meta Plus Patch (Indomethacin)

Adult dosage

Apply to the affected area twice a day.

This medication should not be administered to certain patients. For example, patients who are allergic to this drug or other indomethacin formulations, or have a history of hypersensitivity should not use it. Additionally, patients who have experienced asthma attacks due to aspirin or non-steroidal anti-inflammatory analgesics can also experience severe asthma attacks when using this medication, therefore they should avoid it. Patients who have had bronchospasm, rhinitis, or angioedema with aspirin or other non-steroidal anti-inflammatory analgesics should not use this medication, nor should children under the age of 14. Patients with bronchial asthma must exercise special caution when using this drug since it may exacerbate asthma symptoms. This medication may cause symptoms such as itching, redness, rash, contact dermatitis, and eczema on the skin. These symptoms usually resolve upon discontinuation of the drug. However, rarely, side effects such as warmth, swelling, flushing, severe allergic reactions, photosensitivity, burning, irritation, dryness, numbness, gastrointestinal discomfort, headache, and dizziness may occur. If symptoms are severe, the use must be stopped immediately. Patients with psoriasis should be cautious as the symptoms may worsen with the use of this medication. Additionally, hypersensitivity reactions such as skin reactions, bronchospasm, and severe hypotension may occur, and rarely, symptoms of aseptic meningitis, including headache, nausea, vomiting, fever, stiff neck, and altered consciousness may also occur. Inhaling the spray form of this medication may irritate the airways and cause discomfort. This medication is a symptomatic treatment for pain and inflammation and does not treat the underlying cause. When used for inflammation with concurrent skin infections, it should be carefully administered along with antibiotics or antifungals, and the condition should be closely monitored. When used for chronic conditions like degenerative arthritis, other treatment methods should also be considered in addition to drug treatment, and side effects should be carefully monitored. Care should be taken as systemic side effects may occur when exceeding the recommended dosage or using it over large areas for extended periods. When used on surgical wounds, caution is needed as hypersensitivity shock may occur. In cases of overdose, interactions may occur with coumarin (involved in blood coagulation), hypoglycemic agents, and thyroid hormones like thyroxine. During the third trimester of pregnancy, this medication should not be used as it may delay delivery, increase the risk of bleeding during childbirth, and have serious effects on the fetus. In the early and mid stages of pregnancy, animal studies did not show fetal toxicity, but safety in humans has not yet been established. This medication may be transmitted through breast milk, so it is advisable for breastfeeding women to avoid its use. Its safety has not been established for children, so its use is not recommended. In cases of overdose, serious symptoms such as nausea, vomiting, abdominal distension, diarrhea, gastrointestinal bleeding, headache, dizziness, confusion, drowsiness, insomnia, fatigue, visual disturbances, convulsions, hypotension, and respiratory distress may occur. In cases of overdose, appropriate treatment and monitoring are needed, including gastric lavage or emetics to remove the drug, the administration of activated charcoal, and the adjustment of electrolyte balance. This medication should not be applied to areas with bleeding disorders, eczema, infections, burns, or wounds on the skin, nor to the eyes or mucous membranes. When applied to areas with skin damage, temporary irritation or numbness may occur, so caution is advised. This medication should be used exclusively as a topical agent and should not be used with an occlusive dressing.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, anaphylaxis, severe allergic reactions, bronchospasm, hypotension, shock, aseptic meningitis, altered consciousness, fever with severe rash, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever, yellowing of skin or eyes (jaundice), profound lethargy

Mild side effects

Itching, redness, rash, contact dermatitis, eczema, warmth, swelling, flushing, photosensitivity, burning, irritation, dryness, numbness, gastrointestinal discomfort, headache, dizziness, nausea, vomiting, abdominal distension, diarrhea, gastrointestinal bleeding, confusion, loss of orientation, drowsiness, insomnia, fatigue, anxiety, visual disturbances, sensory abnormalities, numbness, seizures, hypotension, stiff neck, symptoms of aseptic meningitis (headache, nausea, vomiting, fever,

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it is recommended to store the drug at room temperature between 1 degree and 30 degrees. Storing it this way maintains the drug's efficacy and safety.

Appearance

A sticky substance with a dark yellow color is applied to the lint pad and covered with a release paper.

Package unit

10 sheets/package