Acephin Tablet (Aceclofenac)

Adult dose

As aceclofenac, take 100 mg twice a day every 12 hours. Do not chew or crush the tablet; swallow it whole. Adjust dosage as needed based on symptoms. To minimize cardiovascular adverse reactions, take the lowest effective dose for the shortest duration.

This medication poses a risk of gastrointestinal bleeding in individuals who consume three or more alcoholic beverages daily, thus consultation with a physician or pharmacist is essential. This medication may increase the risk of cardiovascular and cerebrovascular events; therefore, patients with cardiovascular diseases or risk factors should use it cautiously and take the lowest effective dose for the shortest duration possible. This medication may cause serious gastrointestinal adverse reactions, including gastrointestinal bleeding, ulcers, and perforations; thus, individuals with a history of gastrointestinal diseases or the elderly should exercise particular caution and seek immediate treatment if gastrointestinal bleeding symptoms occur. Patients with active peptic ulcers or bleeding, who have allergies to this medication or similar medications, those with a history of asthma or allergic reactions, and those with severe cardiac or renal liver impairment, pregnant women in the late stages of pregnancy, and nursing mothers should not take this medication. Individuals with kidney impairment, heart failure, hypertension, liver impairment, and the elderly should use this medication cautiously; regular blood tests and liver and kidney function assessments are necessary when taken over a prolonged period. Dizziness, drowsiness, and visual disturbances may occur while taking this medication, so it is advisable to avoid driving or operating hazardous machinery. Particularly in late pregnancy, this medication may harm the fetus, so it is recommended that women who are pregnant or planning to become pregnant avoid taking it. This medication may interact with various other drugs; therefore, if other medications are being taken, consultation with a physician is required, especially when used together with anticoagulants, diuretics, antidiabetic agents, lithium, methotrexate, etc. This medication may cause serious skin reactions, such as rashes, itching, or in severe cases, Stevens-Johnson syndrome; if any skin abnormalities appear, the medication should be discontinued immediately and medical advice sought. Safety and efficacy in children and adolescents have not been established, so caution is advised, and the elderly are at greater risk of gastrointestinal bleeding, requiring special attention. In cases of overdose, gastrointestinal irritation, hypotension, respiratory depression, and seizures may occur; thus, immediate contact with a medical institution is necessary for appropriate treatment. This medication must be stored out of reach of children, and care must be taken not to transfer it to another container as this may affect quality.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, anaphylaxis, shock, gastrointestinal bleeding, ulcers, perforation, liver abnormalities (jaundice), severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), acute coronary syndrome, myocardial infarction, stroke, heart failure, palpitations, increased blood pressure, stridor, skin and mucosal syndrome, serious neurological symptoms (headaches, seizures, confusion, etc.), renal failure, nephrotic syndrome, angioedema,

Mild side effects

• Dizziness
• abnormal liver enzyme levels
• itching
• rash
• skin reactions
• anemia
• leukopenia
• thrombocytopenia
• neutropenia
• hemolytic anemia

Store this medication in a tightly closed container to protect it from air and moisture. It is best kept at room temperature between 1 degree and 30 degrees Celsius.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle