Corus Omeprazole Capsule

Adult dose

1) Gastric ulcer: The dose is 20 mg of omeprazole orally once daily. Most ulcers heal within 4 weeks, although the healing period may vary in some patients. If the ulcer has not healed after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other treatments, a dose of 40 mg once daily usually achieves healing within 8 weeks, although the healing period may vary in some patients. If the ulcer recurs, repeat treatment. 2) Short-term treatment of duodenal ulcer: Take 20 mg orally once daily. Most ulcers heal within 2 weeks, although the healing period may vary in some patients. If the ulcer has not healed after the initial 2 weeks of treatment, continue treatment for an additional 2 weeks. In patients who have not responded to other treatments, a dose of 40 mg once daily usually achieves healing within 4 weeks, although the healing period may vary in some patients. If the ulcer recurs, repeat treatment. 3) Treatment of reflux esophagitis and symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): - Reflux esophagitis: Take 20 mg orally once daily. Most cases heal within 4 weeks, although the healing period may vary in some patients. If the condition has not healed after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other treatments, a dose of 40 mg once daily usually achieves healing within 8 weeks, although the healing period may vary in some patients. If the condition recurs, repeat treatment. - Treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): Take 20 mg orally once daily. Treatment for 2–4 weeks is generally sufficient for healing. 4) Maintenance treatment of severe reflux esophagitis and peptic ulcers that are difficult to treat: Take 20 mg orally once daily. If the condition recurs, the dose may be increased to 40 mg once daily. 5) Zollinger-Ellison syndrome: The initial dose is 60 mg orally once daily. Continue treatment, adjusting the dose as appropriate for each patient. More than 90% of patients respond to doses of 20–120 mg daily. If doses of 80 mg or more per day are given, divide the daily dose into 2 doses. 6) Antibiotic combination therapy to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: - Dual therapy: Take this medicine 20 mg with amoxicillin 750–1000 mg twice daily for 2 weeks. - Triple therapy: Take this medicine 40 mg once daily or 20 mg twice daily in combination with the following antibiotics: ① Take clarithromycin 250 mg and metronidazole 400 mg twice daily for 1 week, or ② take amoxicillin 1 g and clarithromycin 500 mg twice daily for 1 week. If the treatment response is inadequate, omeprazole monotherapy may be continued. 7) Treatment of gastric or duodenal ulcers or erosions caused by nonsteroidal anti-inflammatory drugs (NSAIDs): Take 20 mg orally once daily. Most cases heal within 4 weeks, although the healing period may vary in some patients. If the condition has not healed after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. 8) Maintenance prevention of gastric or duodenal ulcers or erosions and dyspeptic symptoms caused by NSAIDs in patients receiving long-term NSAID treatment who have a history of gastric or duodenal lesions: Take 20 mg orally once daily. 9) Prevention of recurrence of reflux esophagitis: To prevent recurrence of reflux esophagitis, take 10 mg orally once daily. * Swallow this medicine whole with at least half a glass of water. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used by individuals who are allergic to its ingredients. Caution should be exercised when administering this medication to patients with gastric ulcers who might have malignancies, as it may mask symptoms and delay diagnosis. Additionally, its use with certain antiviral agents may lead to compromised drug effects, thus concurrent use should be avoided. In patients with decreased liver function or elderly patients, the dosage should be reduced, and caution is advised. This medication may cause neurological symptoms such as headache, drowsiness, and dizziness; rarely, it can cause liver dysfunction or severe skin reactions. Gastrointestinal disturbances may cause diarrhea, abdominal pain, or nausea; if skin rash or itching occurs, use should be discontinued immediately. Long-term use of this medication may increase the risk of bone fractures, so it is advisable to take it for the minimum necessary duration. Prolonged use may lead to decreased serum magnesium levels, necessitating regular blood tests. When taken with other medications, interactions may occur, so physicians or pharmacists must be informed of all concurrent medications. Women who are pregnant or breastfeeding should consult a physician before using this medication, and it is preferable to avoid use during breastfeeding. There is insufficient evidence of safety for use in children, so it is best not to administer to them. In cases of overdose, symptoms like vomiting, diarrhea, or headache may occur, hence prescribed dosages should be followed. This medication should be stored out of reach of children and kept in its original container. If a skin rash or severe allergic reaction occurs, it is crucial to discontinue medication immediately and consult healthcare professionals.

Headache, drowsiness, dizziness, insomnia, paresthesia, fainting sensation, lightheadedness, confusion, agitation, aggression, hallucinations, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, intestinal obstruction, constipation, nausea, vomiting, abdominal pain, abdominal bloating, dry mouth, stomatitis, gastrointestinal candidiasis, erythema, rash, hives, itching, dermatitis, vesicular rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, arthralgia, muscle weakness, myalgia, gynecomastia, cough, weakness, fatigue, peripheral edema, increased sweating, visual impairment, vision disorders, taste disorders, breast pain, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile-associated diarrhea, hypomagnesemia, acute generalized exanthematous pustulosis, drug reactions with eosinophilia and systemic symptoms, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyps, hypocalcemia, hypokalemia

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it should be stored in a place avoiding extremes of temperature, ideally between 1 and 30 degrees Celsius.

Appearance

Domestic Use: Hard capsules with a reddish-brown upper part and a pink lower part, filled with white to grayish-white delayed-release granules. Export Use: Hard capsules with a reddish-brown upper part and a pink lower part, filled with white to grayish-white delayed-release granules.

Package unit

Domestic Use: 30 capsules/bottle, 300 capsules/bottle. Export Use: 100 capsules (10 capsules/PTP x 10), 30 capsules (10 capsules/PTP x 3)