Gyeongboranidine Tablet 150 mg (Ranitidine Hydrochloride)

Adult dose

For adults, as ranitidine, take 150 mg orally twice a day, in the morning and at bedtime. For the treatment of gastric and duodenal ulcers, it can be taken as 150 mg twice daily or 300 mg once daily at bedtime; for duodenal ulcer patients, 300 mg can be taken twice daily. For patients with recurrent ulcers, a maintenance dose of 150 mg can be taken once daily at bedtime. For gastroesophageal reflux disease, a dose of 150 mg can be taken twice daily for 8 weeks.

Child dose

For children aged 8 to 18 years, 150 mg can be administered once (2 mg/kg body weight), up to twice a day.

This medication should not be used in patients who have had allergic reactions to this medication or its ingredients. Also, it should not be administered to patients with a history of acute porphyria as it may worsen symptoms. Patients with impaired kidney function should be cautious as this medication can remain in the body longer and lead to side effects, necessitating dosage reduction or increased dosing intervals. Patients with decreased liver function should also be monitored closely. Patients with a history of drug allergies and the elderly should use this medication carefully. Particular caution is necessary for patients taking non-steroidal anti-inflammatory drugs (NSAIDs), and regular health status monitoring is needed. This medication can mask symptoms of gastric cancer, therefore patients with gastric ulcers or those over middle age who have recently developed dyspepsia should confirm the absence of gastric cancer before use. Patients with gastric or duodenal ulcers infected with Helicobacter pylori should undergo eradication therapy. Rarely, severe allergic reactions or shock may occur with this medication, so symptoms should be monitored closely. If symptoms such as hives, rash, breathing difficulties, or hypotension appear, immediately discontinue the medication and consult a physician. Various side effects, including blood disorders, impaired liver function, heart rhythm problems, gastrointestinal disturbances, and neurological symptoms, can occur infrequently, so it is important to report any unusual symptoms immediately. In particular, patients with impaired kidney function may be more susceptible to neurological side effects and should be cautious. If this medication is ineffective, it is advisable to switch to other treatment options, and regular blood, liver, and kidney function tests are recommended for safety. The elderly or patients with chronic lung diseases, diabetes, or weakened immune systems may have an increased risk of pneumonia. If dizziness or drowsiness occurs during treatment, one should avoid driving or operating dangerous machinery. This medication may interact with other drugs, so patients should disclose any medications they are taking. Especially when taken with anticoagulants, blood coagulation status should be frequently checked. Taking high doses of sucralfate concomitantly may reduce absorption, so it's advisable to space doses by more than 2 hours. Pregnant or possibly pregnant women should carefully consider the risks and benefits of using this medication. During breastfeeding, this medication may be transmitted through breast milk, so consultation with a physician is essential before use. Safety in children has not been fully established, therefore caution is needed. Elderly patients are likely to have decreased kidney function, so dosage adjustment and extended dosing intervals may be necessary. This medication may yield false-positive results in urine protein tests, thus adjusting the testing method is advisable. In cases of overdose, vomiting or gastric lavage should be performed to remove the medication, and appropriate treatment should be sought; serious side effects are rare. Keep out of reach of children and avoid transferring to another container. This medication reduces stomach acid secretion, potentially increasing the risk of infections due to bacterial overgrowth, hence caution is warranted. If used long-term, eye-related tests may be required.

Serious side effects

Anaphylactic shock, hives, angioedema, chest pain, hypotension, fever, bronchospasm, shock, angioedema, severe allergic reactions, jaundice, hepatitis, consciousness disturbances, seizures, muscular spasticity, severe neurological symptoms, severe swelling or urination abnormalities, thrombocytopenia, leukopenia, agranulocytosis, pancytopenia, acquired immune hemolytic anemia, bone marrow aplasia, bone marrow suppression, vasculitis, acute interstitial nephritis.

Mild side effects

Hives, angioedema, rash, fever, bronchospasm, hypotension, chest pain, granulocytopenia, elevated serum creatinine levels, leukopenia, thrombocytopenia, bone marrow suppression, aplastic anemia, agranulocytosis, pancytopenia, acquired immune hemolytic anemia, eosinophilia, transient and reversible liver function impairment (elevations in AST, ALT, γ-GTP, ALP levels), bradycardia, heart block, tachycardia, vasculitis.

This medication should be stored in a tightly sealed container to prevent air exposure and kept at room temperature between 1 degree Celsius and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness for a longer period.

Appearance

White round film-coated tablet

Package unit

100 tablets (10 tablets/PTP*10)