Q-Dine Tablet (Ranitidine Hydrochloride)

Adult dose

As ranitidine, 150 mg orally twice daily, in the morning and at bedtime. 1) Gastric and duodenal ulcers: 150 mg orally twice a day, or 300 mg once daily at bedtime. Particularly for patients with duodenal ulcers, 300 mg can be taken twice daily in the morning and at bedtime. 2) Gastroesophageal reflux disease: 150 mg orally twice daily for 8 weeks, or 300 mg orally once daily before bedtime.

Child dose

For ages 8 to 18 years, the dose can be 150 mg once (2 mg per kg of body weight), twice daily.

This medication should not be taken by individuals allergic to this medication or its components. People with a rare disease known as acute porphyria may also experience worsening symptoms if they take this medication, so they should avoid it. Individuals with a hereditary condition that prevents lactose digestion should not take this medication due to the lactose it contains. Caution is needed for those with poor kidney function, as this medication may accumulate in the body, leading to increased blood concentration; dosage should be reduced or intervals between doses increased. Those with weakened liver function should also use this medication carefully. Individuals with a history of drug allergies should be cautious when taking this medication. Elderly individuals should take care, as body functions may be impaired. When using non-steroidal anti-inflammatory drugs concurrently, especially in the elderly or in those with a history of peptic ulcers, regular monitoring is required. This medication may mask symptoms of gastric cancer, so those with gastric ulcers or individuals over middle age displaying new dyspeptic symptoms should confirm whether there is a malignant condition before taking it. Patients with gastric or duodenal ulcers infected with Helicobacter pylori should also receive bacterial treatment. Though rare, severe allergic reactions or shock can occur with this medication; if any unusual symptoms appear, discontinue use immediately and go to a hospital. If allergic symptoms such as hives, rash, or respiratory distress occur, stop taking the medication and seek medical advice. If any symptoms of blood abnormalities such as fatigue, bleeding, or fever appear, blood tests are necessary; if abnormalities are found, discontinue the medication. If symptoms of liver dysfunction or jaundice occur, discontinue the medication immediately. Circulatory problems such as arrhythmias or vasculitis can also occur, although rarely, so caution is warranted. Gastrointestinal symptoms such as constipation, nausea, abdominal pain may occur, and in severe cases, consult medical personnel immediately. Reports have also mentioned neurological symptoms such as dizziness, drowsiness, headaches, and confusion; if these symptoms occur, discontinue use and consult a doctor. Endocrine symptoms such as gynecomastia and erectile dysfunction have also been reported, albeit rarely. For musculoskeletal issues such as myalgia or rhabdomyolysis, stop taking the medication and seek medical advice. Skin-related symptoms such as rashes or hair loss may also occur infrequently. During treatment, the condition of the disease should be checked frequently, and the minimum effective dose should be administered; if no effect is observed, a change in treatment should be considered. Elderly patients or those with chronic lung disease or diabetes may have an increased risk for pneumonia, so caution is warranted. If dizziness or drowsiness occurs, avoid driving or operating dangerous machinery. This medication may interact with other drugs, affecting their efficacy or side effects. Especially when taken alongside anticoagulants, frequent checks of blood coagulation status are necessary. Some drugs may interfere with excretion or may impact absorption due to decreased gastric acid secretion, so any concurrent medications should be discussed with a physician or pharmacist. Pregnant women or women who might become pregnant should take this medication cautiously as its safety has not been established and should only be taken when necessary. Breastfeeding mothers should also be cautious, as this medication can pass into breast milk and should only be taken if essential. Safety in children has not been fully established, so caution is needed for pediatric use. The elderly should be cautious about dosage adjustments, as decreased kidney function may lead to prolonged medication retention in the body. Taking this medication may yield false positive results in certain tests, so attention should be paid to test methods. Overdosage is rarely associated with serious issues, but symptomatic treatment like vomiting or gastric lavage may be necessary, and in some cases, dialysis may be required. This medication should be kept out of reach of children, and transferring it to another container should be avoided as it may compromise quality and pose a risk of accidents. Prolonged use may lead to increased bacterial growth in the gastrointestinal tract due to decreased gastric acid secretion, so caution is warranted. Additionally, animal studies suggest the medication may accumulate in ocular tissues, so regular ophthalmologic examinations are advised during extended use.

Serious side effects

Hives, angioedema (severe swelling), chest pain (tightness in the chest), bronchospasm, hypotension, anaphylactic shock (severe allergic reaction), angioedema, acute interstitial nephritis, jaundice, liver dysfunction, hepatitis, bradycardia, atrioventricular block, tachycardia, vasculitis, acute pancreatitis, seizures, altered consciousness, hepatic myoclonus, rhabdomyolysis, acquired immune hemolytic anemia, bone marrow suppression, aplastic anemia, aplastic anemia, aplastic anemia

Mild side effects

• Headaches
• dizziness
• drowsiness
• heaviness
• insomnia
• agitation
• anxiety
• depression
• hallucinations
• reversible blurred vision

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. Proper storage can help maintain the effectiveness of the medication.

Appearance

White, round, film-coated tablet

Package unit

100 tablets (10 tablets/PTP x 10), 150 tablets (10 tablets/PTP x 15)