Coritef Powder

Adult dose

Add a suitable amount of water to the powder in the container to dissolve it first, then add more water to fill up to the 4 L line, and shake well until the entire solution is homogeneous. It can be dissolved in warm water. For oral administration, adults should not sip this drug but should drink 250 mL of the solution quickly every 10 minutes until rectal output is clear or a total of 4 L is consumed.

Child dose

Dissolving in warm water is not recommended. Children over 3 years should take 25 mL of this drug’s solution per body kg orally per hour until rectal output is clear. Through a nasogastric tube

This drug should not be used in patients with known allergies to this drug or its components. It should not be administered to patients with or suspected of having gastrointestinal obstruction or perforation. It is advisable to avoid administering this medication to patients who are dehydrated or have severe heart failure. Patients with colonic diseases such as toxic colitis or toxic megacolon, or patients with atrophy should not use this drug. Caution should be exercised when using it in patients with intestinal obstruction or severe constipation, elderly or frail patients. Close attention is required in patients with issues related to the gag reflex or altered consciousness, or patients receiving administration through a nasogastric tube, as there is a risk of aspiration of the medication into the lungs. Patients with severe abdominal distention or abdominal pain, as well as patients with severe ulcerative colitis, should use this drug cautiously. Rarely, allergic reactions may occur upon using this drug, so symptoms should be observed closely and treated immediately if necessary. Serious side effects such as intestinal perforation, obstruction, or strangulated hernia may occur, necessitating careful monitoring of abdominal conditions. Patients over 60 years of age should be particularly cautious as serious side effects such as gastric mucosal damage, esophageal perforation, cardiac asystole, and pulmonary edema have been reported. The most common side effects are nausea and abdominal distention, and vomiting, abdominal cramps, and anal irritation may also occur, but most are temporary. Hypersensitive reactions such as urticaria, nasal discharge, or dermatitis may manifest as well. There have been reports of increased or irregular heartbeats, elevated blood pressure, edema, and other cardiac issues, so caution is warranted. If significant abdominal pain or bloating occurs, the rate of administration should be slowed or paused, and a medical examination should be sought. If symptoms of fluid or electrolyte imbalance appear, a blood test should be conducted to assess the condition and appropriate treatment should be administered. Patients with impaired kidney function or at risk of electrolyte imbalance should undergo regular kidney function and ECG tests. For patients at high risk of heart disease, it is prudent to consider pre- and post-treatment ECG testing. This drug may induce diarrhea, so adequate hydration is essential. Coadministration with irritating laxatives should be avoided due to increased risk of colonic mucosal damage. Pregnant or breastfeeding women should only use this drug under medical supervision when absolutely necessary, as its safety has not been established. Safety has not been confirmed for children under 3 years, and careful monitoring for symptoms of hypoglycemia or dehydration is advised. Elderly patients should be administered with special care and gradually. In case of overdose, severe diarrhea may occur, necessitating symptomatic treatment such as hydration. Do not mix with other ingredients or fragrances before administration, and the solution should be used within 48 hours of preparation; any leftovers should be discarded. This drug should be stored out of the reach of children and care must be taken to not transfer it to other containers.

Serious side effects

Urticaria, anaphylactic reaction, intestinal perforation, bowel obstruction, strangulated hernia, gastric mucosal damage, esophageal perforation, cardiac asystole, sudden dyspnea with pulmonary edema, aspiration pneumonia findings, respiratory distress, chest tightness, tongue swelling, facial swelling, lip swelling, cardiovascular abnormalities (tachycardia, palpitations, hypertension, arrhythmia, atrial fibrillation, cardiac asystole, acute pulmonary edema, syncope), dehydration, upper GI bleeding due to Mallory-Weiss tear

Mild side effects

• Nausea
• abdominal distention
• vomiting
• abdominal cramps
• anal irritation
• nasal discharge
• dermatitis
• itching
• rash
• fever

This drug should be stored in a tightly sealed container to avoid exposure to air or moisture, preferably at room temperature between 1 to 30 degrees Celsius. By storing it this way, the drug's effectiveness can be maintained for a longer period.

Appearance

A colorless to white powder in a plastic container or a colorless to white powder in a pouch

Package unit

2L: 1 pouch (55.17g) x 4 pouches/carton, 4L: 1 pouch (55.17g) x 8 pouches/carton