Rukpel Tablet (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2: Adults: Administer 60 mg of anhydrous loxoprofen sodium per dose, taken orally 3 times a day. For a single treatment, 60–120 mg may be taken orally. 2. For indication 3: Adults: Administer 60 mg of anhydrous loxoprofen sodium per dose. As a principle, it may be taken twice a day, up to a maximum of 180 mg per day. It is recommended to avoid taking it on an empty stomach.

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume more than three alcoholic drinks per day; therefore, consultation with a doctor or pharmacist is essential. As a non-steroidal anti-inflammatory drug, it may increase the serious cardiovascular risk of thrombosis, myocardial infarction, and stroke, necessitating caution for patients with cardiovascular disease or risk factors. Patients taking this medication should closely monitor for cardiovascular symptoms and consult healthcare professionals immediately if symptoms occur. Additionally, the medication can cause serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforations; therefore, elderly patients or those with a history of gastrointestinal disorders should use it cautiously. If symptoms of gastrointestinal bleeding or ulcers occur during treatment, it is vital to stop taking the medication immediately and seek medical evaluation and treatment. Patients with specific disorders such as peptic ulcers, severe blood abnormalities, liver impairment, kidney disorders, and heart failure should not take this medication. Patients with a history of allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs should also avoid this medication. Pregnant women in their late pregnancy and breastfeeding mothers, as well as individuals with inflammatory bowel disease, should not use this medication. Caution should be exercised when administering this medication to patients with a history of peptic ulcers, poor liver or kidney function, elderly patients, and hypertensive patients, and their conditions should be closely monitored during treatment. This medication can cause hypersensitivity reactions such as skin rashes, hives, difficulty breathing, and low blood pressure; if any symptoms arise, the medication should be stopped immediately. Gastrointestinal symptoms may include abdominal pain, nausea, vomiting, and diarrhea; severe symptoms should prompt immediate consultation with healthcare professionals. Neurological side effects such as drowsiness, dizziness, and headaches can occur, which necessitate attention when driving or operating machinery. Liver dysfunction or kidney impairment may occur, requiring regular check-ups, and if any abnormal signs are detected, the treatment should be stopped. This medication may interact with other non-steroidal anti-inflammatory drugs, anticoagulants, diuretics, lithium, and methotrexate; therefore, it is critical to inform your healthcare provider of any concurrent medications. This medication should be used cautiously in the early and mid-stages of pregnancy, and it should never be taken in the late pregnancy as it may harm the fetus. It is safe not to take this medication while breastfeeding. Safety for children has not been established, so it is recommended not to administer it to children. Elderly patients are at increased risk for adverse reactions when taking this medication, so additional caution is warranted. Keep this medication out of reach of children and do not transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, mucosal pain in the mouth/eyes, breathlessness, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of the skin or eyes), severe lethargy, sudden severe headaches, lightning headaches, seizures, confusion, visual disturbances, paralysis, urination changes.

Mild side effects

• Itching
• fever
• abdominal pain
• discomfort in the stomach
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation
• chest burning sensation

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius to effectively preserve the drug's efficacy and safety.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle