Medication info

Neotidin Tablets 150 mg (Ranitidine Hydrochloride)

Prescription medicationApproval withdrawn
Ingredient · strength
Ranitidine Hydrochloride›Strength being verified
Manufacturer / importer
구주제약(주)
Appearance
White round film-coated tablets
Packaging
100 tablets (10 tablets/PTP*10)/case, 300 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 200403062 · Notified 2004.06.30

This product's status changed to Approval withdrawn on 2023.06.02. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of gastric ulcers and gastric mucosal lesions, relief of excessive stomach acid
Who uses it
Adults · Children
Adult dosage
As ranitidine, take 150 mg orally 2 times a day, in the morning and before bedtime. 1) Gastric and duodenal ulcers: Take 150 mg orally 2 times a day or 300 mg once a day at bedtime. Particularly, for duodenal ulcer patients, taking 300 mg 2 times a day, in the morning and at bedtime, can improve the treatment rate. 2) Gastroesophageal reflux disease: For 8 weeks, take 150 mg orally 2 times a day, or take 300 mg once a day before bedtime.
Children's dosage
For children aged 8 to 18 years, a single dose of 150 mg (2 mg per kg of body weight), up to 2 times a day can be administered.

Ingredients

Manufacturer
구주제약(주)

Efficacy & effects

Improvement of gastric ulcers and gastric mucosal lesions, relief of excessive stomach acid

  • Gastric and duodenal ulcers
  • Zollinger-Ellison syndrome
  • gastroesophageal reflux disease
  • Mendelson's syndrome
  • post-surgical ulcers
  • gastric and duodenal ulcers caused by NSAID administration
  • gastric mucosal lesions
  • erosion
  • hemorrhage
  • redness
  • swelling
  • acute gastritis
View approved original text

This medication is used for the treatment of gastric and duodenal ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease. It also helps prevent Mendelson's syndrome before anesthesia and ulcer prevention after surgery. Additionally, it is effective for gastric and duodenal ulcers caused by the use of nonsteroidal anti-inflammatory drugs (NSAIDs). It aids in the improvement of gastric mucosal lesions such as exacerbations of acute and chronic gastritis, upper gastrointestinal bleeding, erosion, hemorrhage, redness, and swelling. It is used to relieve symptoms of heartburn and acid regurgitation due to excessive stomach acid, thereby improving patients' overall gastric health.

Dosage and Administration

Adult dosage

As ranitidine, take 150 mg orally 2 times a day, in the morning and before bedtime. 1) Gastric and duodenal ulcers: Take 150 mg orally 2 times a day or 300 mg once a day at bedtime. Particularly, for duodenal ulcer patients, taking 300 mg 2 times a day, in the morning and at bedtime, can improve the treatment rate. 2) Gastroesophageal reflux disease: For 8 weeks, take 150 mg orally 2 times a day, or take 300 mg once a day before bedtime.

Children's dosage

For children aged 8 to 18 years, a single dose of 150 mg (2 mg per kg of body weight), up to 2 times a day can be administered.

Precautions

This medication should not be used in patients with a history of allergic reactions to this drug or its components. Administration should also be avoided in patients with a history of acute porphyria, as this drug may induce acute attacks. In patients with impaired renal function, the blood concentration of this medication may increase, so dosage adjustment or prolonging the administration interval may be required. Patients with liver dysfunction should also use this medication with caution. Patients with a history of drug allergies, the elderly, and those taking nonsteroidal anti-inflammatory drugs should regularly monitor their condition. Gastric cancer symptoms can be masked, so patients with gastric ulcers or middle-aged patients with recent changes in dyspeptic symptoms should confirm the absence of malignant diseases before using this medication. For patients with positive Helicobacter pylori in gastric or duodenal ulcers, bacterial eradication therapy should be conducted concurrently. This medication may rarely cause serious allergic reactions or blood abnormalities, liver dysfunction, heart problems, gastrointestinal symptoms, neurological abnormalities, skin rashes, etc., so if any unusual symptoms occur, discontinue use immediately and seek medical attention. Regular monitoring of patients' blood, liver, and kidney functions during treatment is important. In particular, elderly patients or those with chronic lung disease, diabetes, or weakened immunity may have a higher risk of pneumonia. Avoid driving or operating dangerous machinery if dizziness or drowsiness occurs. This medication may interact with other drugs, so inform your doctor or pharmacist if you are taking any other medications. Pregnant women or those who may become pregnant, as well as breastfeeding women, should use this medication cautiously only when necessary. The safety in children has not been adequately confirmed, so caution is needed. Elderly patients may have increased blood concentration due to decreased kidney function, necessitating dosage adjustments. Some tests may yield false-positive results while taking this medication, so this should be considered during testing. Although overdose rarely leads to specific toxic symptoms, appropriate treatment such as vomiting or gastric lavage is necessary, and in some cases, hemodialysis may be required. This medication should be kept out of reach of children and transferring it to another container can negatively affect quality. Prolonged use may affect the eyes, so an eye examination may be necessary. Finally, using this medication may reduce gastric acid secretion, increasing the risk of bacterial proliferation in the gastrointestinal tract.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • angioedema
  • bronchospasm
  • chest pain
  • anaphylactic shock
  • leukopenia
  • thrombocytopenia
  • bone marrow suppression
  • aplastic anemia
  • agranulocytosis
Show 15 more
  • hypoplastic anemia
  • acquired immune hemolytic anemia
  • jaundice
  • hepatitis
  • angioedema
  • acute pancreatitis
  • seizures
  • altered consciousness
  • myoclonus
  • rhabdomyolysis
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • aplastic anemia
  • heart block
  • acute interstitial nephritis

Mild side effects

  • Rash
  • fever
  • low blood pressure
  • elevated serum creatinine levels
  • bradycardia
  • atrioventricular block
  • tachycardia
  • vasculitis
  • constipation
  • nausea
Show 28 more
  • vomiting
  • abdominal bloating
  • abdominal pain
  • loss of appetite
  • diarrhea
  • dizziness
  • drowsiness
  • headache
  • heaviness in the head
  • insomnia
  • excitement
  • anxiety
  • mental confusion
  • depression
  • hallucination
  • blurred vision
  • involuntary movement disorders
  • gynecomastia
  • excessive milk secretion
  • erectile dysfunction
  • decreased libido
  • joint pain
  • muscle pain
  • muscle aches
  • fatigue
  • skin rash
  • erythema multiforme
  • hair loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air and moisture. It is best to keep it in a dry place at room temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablets

Package unit

100 tablets (10 tablets/PTP*10)/case, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.