Meprasole Capsule (Omeprazole)

Adult dose

1) Gastric ulcer: Administer 20mg of omeprazole orally once daily. Most ulcers heal within 4 weeks, although the healing period may occasionally vary from patient to patient. If healing is not complete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medications, a dose of 40mg once daily usually results in healing within 8 weeks, although the healing period may occasionally vary from patient to patient. If the ulcer recurs, repeat treatment. 2) Short-term treatment of duodenal ulcer: Administer 20mg orally once daily. Most ulcers heal within 2 weeks, although the healing period may occasionally vary from patient to patient. If healing is not complete after the initial 2 weeks of treatment, continue treatment for an additional 2 weeks. In patients who have not responded to other medications, a dose of 40mg once daily usually results in healing within 4 weeks, although the healing period may occasionally vary from patient to patient. If the ulcer recurs, repeat treatment. 3) Treatment of symptoms of reflux esophagitis and gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): - Reflux esophagitis: Administer 20mg orally once daily. Most cases heal within 4 weeks, although the healing period may occasionally vary from patient to patient. If healing is not complete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medications, a dose of 40mg once daily usually results in healing within 8 weeks, although the healing period may occasionally vary from patient to patient. If the condition recurs, repeat treatment. - Treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): Administer 20mg orally once daily. Treatment for 2～4 weeks is generally sufficient for healing. 4) Maintenance therapy for severe reflux esophagitis and peptic ulcers that are difficult to treat: Administer 20mg orally once daily. If the condition recurs, the dose may be increased to 40mg once daily. 5) Zollinger-Ellison syndrome: The initial dose is 60mg orally once daily. Continue treatment, adjusting the dose as appropriate for the individual patient. More than 90% of patients respond to doses of 20 - 120mg daily. If administering more than 80mg daily, divide the dose into 2 doses per day. 6) Concomitant antibiotic therapy to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: - Dual therapy: Administer this medicine 20mg with amoxicillin 750 - 1000mg twice daily for 2 weeks. - Triple therapy: Administer this medicine 40mg once daily or 20mg twice daily in combination with the following antibiotics. ① Administer clarithromycin 250mg and metronidazole 400mg twice daily for 1 week, or ② Administer amoxicillin 1g and clarithromycin 500mg twice daily for 1 week. If the treatment response is insufficient, omeprazole monotherapy may be continued. 7) Treatment of gastric or duodenal ulcers or erosions caused by nonsteroidal anti-inflammatory drugs (NSAIDs): Administer 20mg orally once daily. Most cases heal within 4 weeks, although the healing period may occasionally vary from patient to patient. If healing is not complete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. 8) Maintenance therapy for prevention of gastric or duodenal ulcers or erosions and dyspeptic symptoms caused by NSAIDs in patients receiving long-term NSAID treatment who have a history of gastric or duodenal lesions: Administer 20mg orally once daily. 9) Prevention of recurrence of reflux esophagitis: To prevent recurrence of reflux esophagitis, administer 10mg orally once daily. Swallow this medicine whole with at least half a glass of water. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used by individuals who are allergic to any of its components. Caution is advised when prescribing this medication to patients with gastric ulcers suspected of being malignant, as it may conceal symptoms or delay diagnosis. It cannot be taken with certain antiviral medications, so be sure to inform the healthcare provider about any medications being taken. Patients with lactose intolerance or certain hereditary metabolic disorders should not use this medication. Patients with impaired liver function should adjust the dosage, especially those with severe liver damage, who should not exceed 20mg per day. Elderly patients may respond differently to the medication, so it should be used carefully. Neurocognitive symptoms such as headache, drowsiness, dizziness, and insomnia may occur, and in severe cases, confusion or hallucinations may develop. Elevations in liver enzyme levels or, rarely, serious liver issues such as hepatitis or liver failure can occur, so report any unusual symptoms immediately. It may affect the kidneys, so consult with a healthcare provider if there are changes in urine output or swelling. Gastrointestinal disturbances such as dyspepsia, diarrhea, constipation, nausea, vomiting, and abdominal pain may frequently occur. Skin rashes, itching, urticaria, and in severe cases, serious skin reactions such as Stevens-Johnson syndrome may occur, so discontinue use if skin abnormalities appear. Allergic reactions such as angioedema, fever, and difficulty breathing may rarely occur. Be alert for symptoms such as abnormal heart rhythms or chest pain. A decrease in blood cell counts may also occur, so report any easy bleeding or bruising. Muscle pain or joint pain may develop. Long-term use may lower serum magnesium levels, so regular testing and supplementation may be necessary. Long-term use of this medication may slightly increase the risk of infections due to an increase in the number of bacteria in the stomach, so report any persistent diarrhea to a healthcare provider. There are interactions with certain medications, so inform the healthcare provider about all medications being taken, especially anticoagulants, anticonvulsants, and immunosuppressive agents. Use during pregnancy can affect the fetus; therefore, it must be administered after consulting a physician, and during breastfeeding, either avoid administration or discontinue breastfeeding. The safety of this medication is not established for use in children, so it is advisable not to use it in this age group. In case of overdose, symptoms such as vomiting, diarrhea, headache, and confusion may occur, so seek immediate medical assistance if symptoms are severe. Store the medication out of reach of children, do not transfer it to another container, and keep it tightly closed after use.

Headache, drowsiness, dizziness, insomnia, dysesthesia, feeling of faintness, vertigo, confusion, agitation, aggressiveness, hallucinations, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, colitis, constipation, nausea, vomiting, abdominal pain, abdominal bloating, dry mouth, stomatitis, gastrointestinal candidiasis, erythema, rash, urticaria, itching, dermatitis, vesicular rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, arthralgia, muscle weakness, myalgia, gynecomastia, cough, asthenia, lethargy, peripheral edema, increased sweating, blurred vision, visual impairment, taste disorder, breast pain in women, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile-associated diarrhea, hypomagnesemia, acute generalized exanthematous pustulosis, drug reactions with eosinophilia and systemic symptoms, systemic lupus erythematosus, discoid lupus erythematosus, gastric polyp, hypocalcemia, hypokalemia

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is between 1 and 30 degrees Celsius at room temperature. This will help maintain the medication's effectiveness for an extended period.

Appearance

A hard capsule with an upper part in reddish-brown and a lower part in pink, filled with enteric-coated granules of pale yellow color.

Package unit

28 capsules/bottle, 100 capsules/bottle