Solefen Tablets (Loxoprofen Sodium Hydrate)

Adult dose

1. For efficacy 1 and 2 Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally 3 times a day. For single-use therapy, 60–120 mg may be administered orally at one time. 2. For efficacy 3 Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally. In principle, may be administered twice a day, with a maximum of 180 mg per day. Preferably avoid taking on an empty stomach.

This medication should be discussed with a doctor or pharmacist before use by individuals who regularly consume more than three alcoholic drinks daily, as it may increase the risk of gastrointestinal bleeding. It may also increase the risk of cardiovascular diseases, so patients with a history of heart disease or stroke, or those with risk factors should be especially cautious. Any cardiovascular symptoms should be reported to medical personnel immediately. Serious gastrointestinal problems such as gastrointestinal bleeding, ulcers, and perforations can occur with this medication, thus elderly individuals or those with a history of gastrointestinal disorders should exercise particular caution. Should symptoms of gastrointestinal bleeding occur during treatment, immediate medical attention is required. Patients with a history of peptic ulcers, severe blood disorders, liver or kidney impairment, or who have allergies to any components of this drug should not take it. Individuals with asthma, aspirin allergies, expectant mothers in the later stages of pregnancy, breastfeeding women, or patients with inflammatory bowel disease should also refrain from using this medication. Patients with a history of peptic ulcers, liver or kidney issues, elderly individuals, those with hypertension, or patients with bleeding disorders should use this medication cautiously and require regular monitoring. If skin rash, shortness of breath, or hypotension develops during use, the medication should be stopped immediately and medical personnel notified. This drug may cause various side effects, such as gastrointestinal bleeding, liver function abnormalities, kidney dysfunction, heart failure, and dermatological reactions. If any abnormal symptoms occur, medical care should be sought promptly. This medication should not be taken with other non-steroidal anti-inflammatory drugs, as it may interact with certain blood pressure medications, antibiotics, anticoagulants, etc., so patients should inform their healthcare provider of any other medications they are taking. Caution is advised during the early and middle stages of pregnancy, and it should never be used in the later stages of pregnancy. It's also safer to avoid this medication while breastfeeding. The safety for use in children has not been established, thus it should preferably not be used in children. Elderly individuals are at greater risk for side effects, so special caution is advised during use. This medication should be kept out of reach of children and not transferred to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, shock, anaphylaxis-like symptoms, peptic ulcers, bleeding, perforation, hematemesis, melena, gastrointestinal bleeding with shock, intestinal perforation, acute renal failure, liver function impairment (including jaundice), fulminant hepatitis, liver necrosis, liver failure, interstitial pneumonia, asthma attacks, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme.

Mild side effects

• Occasionally rash
• itching
• fever
• abdominal pain
• discomfort in the stomach
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly closed container to prevent air or moisture exposure, at a safe temperature between 1 to 30 degrees Celsius. Proper storage can help maintain the medication's effectiveness.

Appearance

White round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle