Medication info
Withers Doxazosin Mesylate Tablet 2 Milligrams

Withers Doxazosin Mesylate Tablet 2 Milligrams

Prescription medicationTabletOral
Ingredient · strength
Doxazosin Mesylate›2.43mg / 1 tablet
Manufacturer / importer
Withus Pharmaceutical Co., Ltd.
Appearance
For domestic use: white rectangular tablet For export: white rectangular tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200402842 · Notified 2004.08.23 · Insurance code 660701160

Summary

Main use
Treatment of symptoms of benign prostatic hyperplasia (e.g., difficulty urinating) and hypertension
Who takes it
Adults
Adult dose
○ Adults 1. Hypertension: Administer doxazosin orally once daily at an initial dose of 1㎎, and increase to 2㎎ after 1 week according to the patient's response. To achieve the desired blood pressure control, the dose may be increased gradually at intervals of 1-2 weeks to 4㎎, 8㎎, and 16㎎ daily. If blood pressure cannot be controlled with this drug alone, it may be administered in combination with a thiazide diuretic or β-blocker. 2. Urinary retention and voiding disorders due to benign prostatic hyperplasia: The initial dose is 1㎎ once daily. Depending on the patient's blood pressure, the daily dose may be increased to 2㎎ at intervals of 1-2 weeks, and may be increased gradually to 4㎎ and 8㎎. ᛫ Adjust the dose according to age and symptoms.

Ingredients

Manufacturer
Withus Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of symptoms of benign prostatic hyperplasia (e.g., difficulty urinating) and hypertension

  • Hypertension
  • urinary obstruction
  • urination disorders
View approved original text

This medication is used to control hypertension, that is, high blood pressure, and also helps improve urination problems or urinary obstruction symptoms caused by benign prostatic hyperplasia. Thus, it is effectively used for issues related to hypertension and prostatic enlargement.

How to take

Adult dose

○ Adults 1. Hypertension: Administer doxazosin orally once daily at an initial dose of 1㎎, and increase to 2㎎ after 1 week according to the patient's response. To achieve the desired blood pressure control, the dose may be increased gradually at intervals of 1-2 weeks to 4㎎, 8㎎, and 16㎎ daily. If blood pressure cannot be controlled with this drug alone, it may be administered in combination with a thiazide diuretic or β-blocker. 2. Urinary retention and voiding disorders due to benign prostatic hyperplasia: The initial dose is 1㎎ once daily. Depending on the patient's blood pressure, the daily dose may be increased to 2㎎ at intervals of 1-2 weeks, and may be increased gradually to 4㎎ and 8㎎. ᛫ Adjust the dose according to age and symptoms.

Precautions

This medication can cause orthostatic hypotension, therefore dizziness or fainting may occur when starting the medication or increasing the dose, or when stopping and then resuming it. Therefore, it is important to start with a low dose and gradually adjust the dose. This medication can rarely cause a condition called priapism, which, if not treated early, can lead to permanent erectile dysfunction, so caution should be exercised. Patients with allergies to this drug or similar ingredients, leukopenia, hypotension, children under 12 years of age, and those with certain genetic lactose metabolism abnormalities should not use this medication. Patients with liver function problems should use this drug cautiously, monitoring for adverse reactions through blood tests and other means. This medication can cause various side effects including dizziness, headache, drowsiness, nausea, hypotension, palpitations, shortness of breath, and rash, among others, so if symptoms are severe or unusual, immediate consultation with a healthcare provider is advised. When taking this medication, it is important to move slowly when getting up suddenly, and if symptoms of dizziness or hypotension occur, it is vital to lie down and rest immediately. Also, caution should be exercised while driving or operating hazardous machinery. If taken with other antihypertensive agents or diuretics, or certain erectile dysfunction treatments, the risk of hypotension may increase, so it is essential to consult with a physician. Women who are pregnant or breastfeeding should only use this medication under a doctor's judgment as its safety has not been established, and breastfeeding should be avoided when possible. Special caution is needed when administering to children or the elderly, as safety has not been adequately confirmed or the risk of side effects may be higher. In case of overdose, severe hypotension may occur, so lay down with your head low immediately and seek appropriate treatment at a hospital if necessary. This medication must be stored out of reach of children, and it is recommended not to transfer it to other containers to ensure safety and maintain quality.

Side effects

Syncope, dizziness, agranulocytosis, leukopenia, neutropenia, thrombocytopenia, headache, drowsiness, anxiety, insomnia, dry mouth, fatigue, seizures, heaviness in the head, numbness, lethargy, weakness, loss of consciousness, visual disturbances, tinnitus, olfactory disturbances, pain, nausea, vomiting, diarrhea, constipation, dyspepsia, abdominal bloating, gastric discomfort, loss of appetite, dry mouth, orthostatic hypotension, hypotension, palpitations, arrhythmia, tachycardia, peripheral vascular ischemia, edema, chest tightness, angina, myocardial infarction, cerebrovascular disorders, dyspnea, rhinitis, nosebleed, polyuria, frequent urination, urinary incontinence, erectile dysfunction, low back pain, urinary tract infection, priapism, chest pain, joint pain, myalgia, elevated AST, elevated ALT, elevated ALP, elevated LDH, sweating, rash, itching, nasal congestion, facial flushing, sensory impairment, gynecomastia, allergic reactions, bradycardia, hepatitis, cholestatic hepatitis, worsening of bronchospasm, urticaria, hematuria, voiding dysfunction, nocturia, intraoperative pupillary dilation syndrome

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

For domestic use: white rectangular tablet For export: white rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.