Omezon Capsule (Omeprazole)

Adult dose

1. Gastric ulcer: Administer omeprazole 20mg orally once daily. Most ulcers heal within 4 weeks, although healing time may occasionally vary by patient. If healing is incomplete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medications, a dose of 40mg once daily usually results in healing within 8 weeks, although healing time may occasionally vary by patient. If the ulcer recurs, repeat treatment. 2. Short-term treatment of duodenal ulcer: Administer 20mg orally once daily. Most ulcers heal within 2 weeks, although healing time may occasionally vary by patient. If healing is incomplete after the initial 2 weeks of treatment, continue treatment for an additional 2 weeks. In patients who have not responded to other medications, the healing time may vary. If the ulcer recurs, repeat treatment. 3. Treatment of symptoms (heartburn, regurgitation, etc.) of reflux esophagitis and gastroesophageal reflux disease (GRED): 1) Reflux esophagitis: Administer 20mg orally once daily. Most cases heal within 4 weeks, although healing time may occasionally vary by patient. If healing is incomplete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other medications, a dose of 40mg once daily usually results in healing within 8 weeks, although healing time may occasionally vary by patient. If the condition recurs, repeat treatment. 2) Treatment of symptoms (heartburn, regurgitation, etc.) of gastroesophageal reflux disease (GERD): Administer 20mg orally once daily. Treatment for 2～4 weeks generally results in healing. 4. Maintenance therapy for severe reflux esophagitis and peptic ulcers that are difficult to treat: Administer 20mg orally once daily. If the condition recurs, the dose may be increased to 40mg once daily. 5. Zollinger-Ellison syndrome: The initial dose is 60mg orally once daily. Continue treatment, adjusting the dose as appropriate for the individual patient. More than 90% of patients respond to doses of 20 - 120mg per day. If administering more than 80mg per day, divide the total daily dose into 2 doses. 6. Concomitant antibiotic therapy to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: 1) Dual therapy: Concomitant antibiotic therapy with this drug 20mg and amoxicillin 750 - 1000mg 2) Triple therapy: Administer this drug 40mg once daily or 20mg twice daily in combination with the following antibiotics. ① Administer clarithromycin 250mg and metronidazole 400mg twice daily for 1 week, or ② Administer amoxicillin 1g and clarithromycin 500mg twice daily for 1 week. If the treatment effect is insufficient, omeprazole monotherapy may be continued. 7. Treatment of gastric/duodenal ulcers or erosions caused by nonsteroidal anti-inflammatory drugs (NSAIDs): Administer 20mg orally once daily. Most cases heal within 4 weeks, although healing time may occasionally vary by patient. If healing is incomplete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. 8. Maintenance prevention of gastric/duodenal ulcers or erosions and dyspeptic symptoms caused by NSAID use in patients receiving long-term NSAID treatment who have a history of gastric/duodenal lesions: Administer 20mg orally once daily. 9. Prevention of recurrence of reflux esophagitis: Administer 10mg orally once daily to prevent recurrence of reflux esophagitis. * Swallow this medicine whole with at least half a glass of water. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used in individuals with a known allergy to its components. It should not be administered to patients with gastric ulcers suspected of being malignant as symptoms may be masked or diagnosis may be delayed. Particularly, patients taking atazanavir or rilpivirine should not use this medication concurrently. Patients with impaired liver function may have slower metabolism of this drug and dosage should be reduced, and caution is needed for the elderly as well. This medication may cause neurological symptoms such as headache, dizziness, drowsiness, and insomnia, and any unusual symptoms should be reported. If there is impaired liver function, liver enzyme levels may increase, necessitating regular monitoring, and in severe cases, discontinuation of treatment may be required. Rarely, it may cause renal problems, so careful observation of renal function is required. Gastrointestinal symptoms such as diarrhea, nausea, and abdominal pain may commonly occur. Skin reactions such as rashes, itching, and in severe cases, serious skin reactions like Stevens-Johnson syndrome may occur, requiring immediate consultation with a doctor. Hypersensitivity reactions such as angioedema or anaphylaxis may occasionally occur as serious allergic reactions. Symptoms such as heart arrhythmias or chest pain may also appear, so caution is necessary. There may be a decrease in blood cell count, requiring blood tests. Long-term use may lead to electrolyte abnormalities, such as hypomagnesemia, necessitating regular tests and supplementation. This medication inhibits gastric acid secretion, which can interfere with the absorption of certain medications, so it is essential to inform the doctor about any concurrent medications. Especially when taking warfarin, diazepam, or phenytoin, it is necessary to monitor blood concentration changes. Women who are pregnant or may become pregnant should carefully consider the benefits and risks of using this medication. If breastfeeding, due to uncertainty regarding the transmission into breast milk, it is advisable to either avoid use or discontinue breastfeeding. The safety in children has not yet been established, so caution is necessary for use in pediatric patients. In case of overdose, symptoms such as vomiting, headache, and dizziness may occur, but they are generally transient and serious outcomes are rare. This medication should be stored out of the reach of children, in its original container, and the cap should be tightly closed after use. Long-term use may exacerbate gastric polyps or autoimmune diseases, so regular check-ups and consultations with a doctor are necessary.

Headache, drowsiness, dizziness, insomnia, paresthesia, feeling faint, lightheadedness, confusion, excitement, aggressiveness, hallucinations, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, melena, constipation, nausea, vomiting, abdominal pain, abdominal distension, dry mouth, stomatitis, gastrointestinal candidiasis, erythema, rash, urticaria, itching, dermatitis, vesicular rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, joint pain, muscle weakness, myalgia, gynecomastia, cough, fatigue, lethargy, peripheral edema, increased sweating, blurred vision, visual impairment, taste disorder, breast pain, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile-associated diarrhea, hypomagnesemia, acute generalized exanthematous pustulosis, eosinophilia, drug reaction with systemic symptoms, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyps, hypocalcemia, hypokalemia

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It should be kept at room temperature, maintaining a temperature between 1 and 30 degrees Celsius.

Appearance

A hard capsule with an upper reddish-brown and lower pink color, filled with pale yellow enteric-coated granules.

Package unit

30 capsules/bottle, 100 capsules/bottle