Amodipine Tablets 5 mg (Amlodipine Besilate)

Adult dose

For amlodipine, take 5 mg orally once a day, and can be increased up to a maximum of 10 mg per day according to the patient's response. Adjustments may be made according to age and symptoms.

Child dose

The oral dosing for effective blood pressure reduction of amlodipine is once a day at 2.5 mg to 5 mg. Doses exceeding 5 mg per day have not been studied in pediatric patients.

This medication should not be used in certain patients. For instance, people allergic to this medication or similar types of drugs, nursing women, patients with severely impaired liver function, patients with severe aortic stenosis, and patients in shock should not be treated. Furthermore, caution is required for severely hypotensive patients, those requiring dialysis due to kidney failure, elderly patients, and women who are pregnant or may become pregnant. This medication generally has good tolerability, but side effects such as facial flushing due to vasodilation, fatigue, leg swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea may occur. More rarely, various adverse reactions such as hypotension, vasculitis, neurological symptoms, erectile dysfunction, gynecomastia, digestive disorders, weight changes, joint pain, muscle cramps, blood cell reduction, insomnia, cough, and skin rashes have been reported. Patients with heart failure may have an increased risk of pulmonary edema when using this medication, and patients with impaired liver function may require dosage adjustments due to increased drug concentrations. This medication takes effect gradually and is not suitable for the treatment of acute angina. It is known not to significantly affect driving or machine operation ability. This medication can interact with various other drugs, so if you are taking other medications, be sure to consult with your doctor or pharmacist. In particular, it is recommended to avoid concomitant use with grapefruit juice as it may enhance the antihypertensive effect. Pregnant or nursing women should only use this medication if there are no alternative medications available, and it is recommended to discontinue breastfeeding. It is recommended for children aged 6 years and older, as safety and efficacy have not been established for those younger. Overdose may result in severe hypotension and tachycardia, requiring immediate emergency treatment. This medication is not removed by blood dialysis, so appropriate measures such as gastric lavage or administration of adsorbents should be taken in the event of an overdose.

Serious side effects

Hives, angioedema, erythema multiforme, toxic epidermal necrolysis, respiratory distress, difficulty breathing, respiratory abnormality accompanied by cough and fever, hepatitis, jaundice, liver abnormal symptoms, severe swelling, significantly reduced urine output

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a container that protects it from light and air and kept at a temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the effectiveness of the medication.

Appearance

White hexagonal tablet

Package unit

30 tablets/box [10 tablets/PTP X 3], 300 tablets/bottle