Roxostar Tablet (Sodium Loxoprofen Hydrate)

Adult dose

1. For indications 1 and 2 60 mg should be taken orally three times a day. For single treatment, 60–120 mg should be taken orally. 2. For indication 3 60 mg should be taken orally, usually twice a day, with a maximum of 180 mg per day. It is preferable to avoid taking it on an empty stomach. The dose should be adjusted appropriately according to symptoms.

This medication should be discussed with a doctor or pharmacist if the patient regularly consumes more than three alcoholic beverages per day, as there is a risk of gastrointestinal bleeding. This medication may cause cardiovascular problems and increase the risk of serious cardiovascular diseases such as myocardial infarction or stroke, so individuals with cardiovascular disease or risk factors should be carefully monitored before use. It may also affect the gastrointestinal tract, posing risks of bleeding, ulcers, or perforation, especially in the elderly, who should exercise caution. Patients with peptic ulcers, severe hematological disorders, liver impairment, kidney impairment, heart failure, or those with hypersensitivity to this drug should not take it. Patients with a history of asthma or allergic reactions should also be cautious when taking this medication, and it is advisable to avoid use during late pregnancy or while breastfeeding, as well as in patients with inflammatory bowel disease. Regular blood tests and assessments of liver and kidney functions are necessary for those taking this medication long-term, and any abnormal symptoms should be reported to a doctor immediately. If symptoms of hypersensitivity such as rash, itching, difficulty breathing, or decreased blood pressure occur while taking this medication, it should be discontinued immediately, and appropriate treatment should be sought. Gastrointestinal symptoms such as abdominal pain, nausea, vomiting, or blood in stool may appear, and medical attention should be sought if these symptoms occur. This medication may cause neurological side effects such as drowsiness, dizziness, and headaches; therefore, caution is required when driving or operating machinery. Liver function impairment or reduced kidney function may occur, and if related symptoms appear, use should be discontinued, and a doctor should be consulted. It is not advisable to take this medication with other non-steroidal anti-inflammatory drugs, and there may be interactions when used with specific blood pressure medications, anticoagulants, diuretics, etc.; therefore, inform a doctor before taking. Use during pregnancy, especially in the late stages, may be harmful to the fetus, and it should also be avoided while breastfeeding. The safety in children has not been established, so caution is advised when using in pediatrics. As the risk of side effects is higher in the elderly, special caution is needed when taking this medication. This medication should be stored out of reach of children and should not be transferred to another container, as it may affect the quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, shock, symptoms resembling anaphylaxis, peptic ulcers, perforation, hematemesis, melena, shock with bleeding, skin and mucous membrane adverse reaction syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), polymorphic erythema, acute generalized exanthematous pustulosis, aseptic meningitis, jaundice, fulminant hepatitis, acute kidney failure, interstitial pneumonia with fever and difficulty breathing

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a sealed container to prevent air or moisture ingress. The appropriate storage temperature is room temperature between 1 degree and 30 degrees, avoiding excessively hot or cold places.

Appearance

Pink round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle