Sicobik Injection (Ascorbic Acid)

Adult administration

As ascorbic acid, 50 to 1,000 mg per day, divided into 1 to multiple subcutaneous, intramuscular, or intravenous injections per day. Adjust according to age and symptoms.

Care must be taken to avoid introducing glass fragments when cutting the glass ampoule, which can cause adverse reactions. This is especially important when administering to children or the elderly. Patients with hypersensitivity to this medication or with certain diseases, such as hyperoxaluria, thalassemia, gout, cystinuria, G6PD deficiency, or kidney stones should not take this medication. In particular, G6PD deficient patients may experience hemolysis with high doses, necessitating caution. When taking this medication, side effects such as nausea, vomiting, diarrhea, heartburn, abdominal cramps, fatigue, flushing, headache, and insomnia may occur. High doses may increase the risk of diarrhea or kidney stones, and diuretic effects may be present. Excessive dosing can lead to the formation of stones in the urinary tract, so caution is necessary. This medication is primarily taken orally, but should only be used as an injection in acute situations or when absorption is difficult. If oral administration is possible, it is advisable to switch back quickly. This medication may interact with other drugs, so caution is necessary when taken with aspirin, alcohol, certain antibiotics, and oral contraceptives. In particular, high doses may reduce the effect of anticoagulants. During pregnancy, its safety for the fetus is not assured, so it should only be used when the benefits outweigh the risks, and high doses should be avoided. During breastfeeding, risks to the baby are considered low at regular doses. This medication can affect the results of some clinical tests, such as urine glucose tests or hematuria tests, so it is essential to inform the healthcare provider about its use when being tested. In cases of overdose, diarrhea or kidney stones may occur, and diuretic effects may arise, so immediate discontinuation and appropriate treatment should be sought. When administered as an injection, pain at the injection site may occur, so the minimum effective dose should be used, avoiding areas where nerves pass and not repeating injections in the same area. Intravenous injections should be administered slowly to reduce dizziness or phlebitis. Lastly, this medication should be stored out of reach of children and kept in a dry place away from direct sunlight, preferably in its original container.

Serious side effects

Hemolysis (possible in G6PD deficient patients)

Mild side effects

• Nausea
• vomiting
• diarrhea
• heartburn
• abdominal cramps
• fatigue
• flushing
• headache
• insomnia
• pain at the injection site

This medication may be sensitive to light, so it should be stored in a tightly sealed container that protects it from light. Additionally, to maintain its effectiveness, it should be stored at refrigeration temperatures between 2°C and 8°C.

Appearance

A brown vial containing a clear, colorless or pale yellow injection solution

Package unit

1 vial (20 mL) × 10