Taeguk Levosulpiride Tablet (Levosulpiride)

Adult dose

Adults: Administer levosulpiride 25 mg orally three times daily before meals.

This medication should not be used by women who are pregnant or may become pregnant, nor by women who are breastfeeding. It should not be administered to patients with gastrointestinal bleeding, mechanical obstruction, or perforation, as this medication may stimulate gastrointestinal motility. It is contraindicated in patients with specific tumors such as pheochromocytoma, as it may exacerbate hypertension. Patients who have allergic reactions to this medication or cannot tolerate it should also avoid use. This medication should not be used in patients with liver disease, manic episodes of bipolar disorder, or patients in the manic phase. Patients with problems involving the mammary glands should exercise caution, as this medication may increase prolactin secretion and cause breast-related abnormalities. This medication contains lactose, so it should not be given to patients with lactose intolerance or related genetic disorders. It should be used cautiously in patients with hypertension, children, and the elderly, and especially in children, excessive doses should be avoided. This medication may cause amenorrhea, excessive lactation, and gynecomastia due to hormonal imbalances; thus, use should be discontinued immediately if any abnormal symptoms appear. Rarely, neurological symptoms such as tremors, tongue twisting, and agitation may occur; the medication should be discontinued if such symptoms arise. Prolonged use may lead to persistent involuntary facial movements, requiring careful monitoring. Gastrointestinal side effects may include dry mouth, heartburn, nausea, vomiting, diarrhea, and constipation. Patients may experience cardiovascular issues such as hypertension or arrhythmias; monitoring is necessary. A rare side effect known as neuroleptic malignant syndrome may occur, presenting with high fever, muscle rigidity, and altered consciousness; if these symptoms appear, the medication must be stopped immediately and professional treatment sought. If a rash or edema occurs, medication use should be discontinued, and symptoms such as flushing, malaise, insomnia, drowsiness, dizziness, unsteadiness, erectile dysfunction may also arise. It is advisable to avoid driving or operating machinery requiring concentration during treatment. Interactions may occur with other medications, particularly anticholinergics, narcotic analgesics, digitalis preparations, other benzamide medications, psychiatric medications, and drugs that prolong the QT interval; caution is required when used together. It should not be used concurrently with drugs that cause electrolyte abnormalities. This medication is not recommended for pregnant or breastfeeding women as safety for the fetus or newborn has not been established. In the elderly, renal function may decline, leading to increased drug concentration; therefore, dose and administration intervals should be adjusted with close monitoring of adverse reactions. This medication has antiemetic properties and may conceal vomiting symptoms caused by other factors, so careful observation is necessary when using it. Animal studies have reported a risk of reproductive function impairment and tumor occurrence with high-dose long-term administration, necessitating caution with prolonged use.

• Amenorrhea
• galactorrhea
• gynecomastia
• tremors
• tongue twisting
• agitation
• oral dyskinesia
• thirst
• heartburn
• nausea

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 degree Celsius and 30 degrees Celsius at room temperature. Proper storage will help maintain the drug's effectiveness and safety over time.

Appearance

White oval tablets

Package unit

30 tablets/bottle, 500 tablets/bottle