Roxofren Tablets (Sodium Loxoprofen Hydrate)

Adult dose

Administer 60 mg orally three times a day. For single-dose therapy, 60 to 120 mg can be taken orally. The dosage can be increased up to a maximum of 180 mg per day, taken twice daily. It is advisable to avoid taking it on an empty stomach. Adjust dosage appropriately according to symptoms.

This medication should be consulted with a doctor or pharmacist if taken regularly by individuals who consume three or more alcoholic drinks per day, as there is an increased risk of gastric bleeding. Patients with cardiovascular diseases or risk factors should be cautious as the risk of complications such as myocardial infarction and stroke may increase. This medication can cause serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforation, especially in elderly patients or those with a history of gastrointestinal diseases. Patients with peptic ulcer, severe liver impairment, kidney impairment, heart failure, or allergies to this medication or its components should not take it. Patients with a history of asthma or allergies may experience severe anaphylactic reactions, so this medication should not be administered to them. Pregnant women in the late stages and breastfeeding mothers should not use this medication, and it should be used with caution during the early to mid-stages of pregnancy as per doctor’s discretion. This medication can cause hypersensitivity reactions such as skin rash, urticaria, and difficulty breathing. If these symptoms occur, the medication should be discontinued immediately, and medical consultation is necessary. Long-term use requires regular monitoring of liver function, renal function, and blood tests, and discontinuation is necessary in case of any abnormalities. Using it together with other non-steroidal anti-inflammatory drugs increases the risk of side effects, so it is advisable not to use them simultaneously. Drug interactions may occur with specific medications, so it is essential to inform healthcare providers about any medications currently being taken. Safety in pediatric patients has not been established, thus it is preferable not to use this medication in children. Elderly patients have a higher risk of side effects, so they should be observed more closely during administration. This medication should be kept out of the reach of children, and it is safer not to transfer it to other containers.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, breathing difficulties accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizure, altered consciousness, visual disturbances, paralysis, urination changes

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a sealed container to prevent air and moisture from entering and kept at a temperature between 1 to 30 degrees Celsius. Proper storage will maintain the effectiveness and prevent deterioration of the medication.

Appearance

White round tablets

Package unit

30 tablets/bottle, 500 tablets/bottle