Simvastatin 20 mg Tablets

Adult dose

Administer 5–40 mg once daily in the evening. The initial starting dose is 20 mg, and in high-risk adults, 40 mg is administered once daily. Patients with homozygous familial hypercholesterolemia receive 40 mg once daily in the evening. There are dose restrictions when used with certain drugs, and for patients with severe renal impairment, the initial dose is 5 mg.

Child dose

For pediatric patients aged 10-17 years, administer 10 mg once daily in the evening, with a maximum dose of 40 mg per day. Dosage adjustments should be made appropriately according to treatment goals with an interval of 4 weeks.

This medication carries a risk of muscle problems, so if muscle pain or weakness occurs, especially when taking a high dose, inform your doctor immediately. This medication may affect liver function, so patients with liver disease or abnormal liver function tests should not take it. Pregnant women, women who may become pregnant, and nursing mothers should not take this medication. If taken with certain other medications, the risk of muscle damage may increase, so it is essential to inform your doctor or pharmacist if you are taking other medications. Excessive alcohol consumption or a history of liver or kidney disease requires careful use of this medication, and regular monitoring may be necessary. Elderly patients and women are at a higher risk of developing muscle problems, so caution is needed. It is advisable to regularly check liver function and muscle condition while taking this medication. Some patients may experience side effects such as headaches, dyspepsia, constipation, nausea, or other symptoms, and if symptoms persist, consult your doctor. It is recommended to avoid taking this medication with grapefruit juice, as grapefruit juice can increase the drug’s blood concentration and the risk of side effects. Avoid taking this medication during pregnancy or nursing, and women planning to become pregnant should consult their doctor before taking it. Inform your doctor if you are starting any new medications while taking this drug. In case of overdose, seek medical attention immediately for appropriate treatment. This medication should be kept out of reach of children and stored in its original container for safety.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blistering, skin peeling, oral/eye mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes, profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine volume

Mild side effects

Abdominal pain, weakness, constipation, diarrhea, dyspepsia, bloating, nausea, headache, upper respiratory infection, atrial fibrillation, gastritis, diabetes, muscle pain, insomnia, dizziness, bronchitis, stenosis, eczema, urinary tract infection, alopecia, itching, skin changes, flat lichen drug rash, gynecomastia, decreased libido, sexual dysfunction, cataract progression, eye muscle paralysis, anemia, thyroid dysfunction, transient liver function test abnormalities, HbA1c and fasting blood

This medication should be stored in a sealed container to protect it from air and moisture. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. This way, the drug's effectiveness and safety can be well preserved.

Appearance

Yellowish-brown oval film-coated tablet

Package unit

30 tablets/bottle