Sameron Tablets (S-Adenosyl-L-Methionine Tosylate)
S-Adenosyl-L-Methionine Sulfate Tosilate 384mg
Prescription medication
Shinpoong Pharmaceutical Co., Ltd.
MFDS item code 200400032 · Notified 2004.08.18
This product's status changed to Approval withdrawn on 2026.01.14. It may no longer be sold, so consult a doctor or pharmacist before taking it.
Treatment of depression
This medication is used for depression.
Depression Initiation therapy: Administer orally 400 mg of S-adenosyl-L-methionine per dose, 2 ∼ 3 times daily, for 15 ∼ 30 days. Maintenance therapy: Administer orally 200 mg per dose, 2 ∼ 3 times daily. Swallow this medicine whole; do not chew or crush it.
This medication should not be used in certain patients. First, individuals with allergies to this drug or its components should avoid taking it. Patients diagnosed with schizophrenia or psychosis should not use this medication. Those with bipolar disorder, characterized by extreme mood swings, should also refrain from taking this drug. It is not administered to children. Women who are pregnant, potentially pregnant, or breastfeeding should not take this medication as a safety precaution. Patients with certain genetic disorders, such as homocystinuria or hyperhomocysteinemia, should also avoid this medication. While taking this medication, various side effects may occur. First, facial swelling, stiffness in the tongue and throat, and difficulty breathing may occur, along with severe allergic reactions such as rapid heartbeat or a sudden drop in blood pressure. Gastrointestinal issues may sometimes present with discomfort, nausea, vomiting, and mild abdominal pain, while constipation, bloating, or indigestion may occur rarely. Skin reactions may include rash, itching, and hives. Additionally, occasional insomnia, dry mouth, headaches, or fatigue may also be experienced. This medication may particularly increase the risk of suicidal behavior in individuals under 25 years of age, so caution is advised. Moreover, there is insufficient clinical data for elderly patients aged 65 and over or those taking this medication long-term, necessitating careful use. There is insufficient experience regarding the safety of this medication during pregnancy, so it is advisable not to use it in such cases. Additionally, there is no information on whether this medication is transmitted through breast milk, so breastfeeding women should also avoid taking it. This medication requires careful storage. If the container is broken, cracked, or if the medication has changed color due to prolonged exposure to heat, it should not be used and should be replaced.
Not everyone experiences these, and they can vary from person to person.
This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. This way, the medication's effectiveness can be preserved longer.
Pale yellow, round enteric-coated tablet
80 tablets (8 tablets/PTP x 10)
Even with the same ingredient, strength, dosage form and how it is taken can differ.
S-Adenosyl-L-Methionine Sulfate Tosilate 384mg
Prescription medication
Shinpoong Pharmaceutical Co., Ltd.

S-Adenosyl-L-Methionine Sulfate Tosilate 384mg
Tablet · Prescription medication
Chodang Pharmaceutical Industry Co., Ltd.
S-Adenosyl-L-Methionine Sulfate Tosilate 192mg
Injections · Prescription medication
Daehan New Pharm Co., Ltd.
S-Adenosyl-L-Methionine Sulfate Tosilate 192mg
Injections · Prescription medication
Nokshim Won Co., Ltd.
Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.