Artlen Capsule 50 Milligrams (Dinaacerein)

Adult dose

Adults: Administer 50∼100mg of diacerein per day orally in 1∼2 divided doses after meals. Adjust the dose appropriately according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used in certain patients. It is not administered to patients with inflammatory bowel disease, patients with intestinal obstruction syndrome, or patients with undiagnosed abdominal pain. Additionally, it should not be used in patients with a history of allergic reactions to this medication or its components, those with liver disease or a history of liver disease, and children under 15 years of age. This medication should be used cautiously in some patients. Extra care is needed for patients with a history of small intestine or colon disease, pregnant or breastfeeding women, and elderly patients over 65 years old, for whom a reduction in dosage may be necessary. While using this medication, attention should be paid to adverse reactions. Gastrointestinal issues may include diarrhea, loose stools, abdominal pain, and long-term use may lead to serious problems such as gastrointestinal bleeding, ulcers, or perforation. If diarrhea worsens, dehydration or fluid and electrolyte imbalances may occur, necessitating caution. Skin reactions such as itching, rash, and eczema are common. In terms of liver function, there may rarely be an increase in liver enzyme levels, so liver health should be monitored. When using this medication for an extended period, it is essential to follow the doctor's instructions. If diarrhea occurs, discontinue administration and consult medical personnel, and avoid using it with laxatives. If there are signs of liver damage, use should be promptly stopped, and the doctor's instructions should be followed; it is advisable to limit alcohol consumption during the course of this medication. This medication may interact with other drugs, so caution is necessary. Taking antacids containing calcium, magnesium, or aluminum, or with salt may interfere with the absorption of this medication, so they should be taken with at least a 2-hour interval. If used with diuretics, the diuretic effect may be enhanced, resulting in dehydration or hypokalemia, necessitating caution. Be cautious as there is an increased risk of arrhythmias when combined with cardiac glycosides. Pregnant or breastfeeding women should refrain from using this medication. Animal studies have reported delays in fetal bone formation, and there is insufficient data on its effects in humans, but some components may be transmitted through breast milk. In case of overdose, severe diarrhea may occur, and appropriate treatment, such as electrolyte supplementation, should be provided as necessary.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, itching, rashes, eczema, elevation of serum liver enzymes

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, the storage temperature should be maintained at room temperature between 1 to 30 degrees Celsius. Proper storage helps to safely preserve the medication's efficacy.

Appearance

A hard capsule with a yellowish-brown content inside, with the upper part being dark yellow and the lower part light yellow.

Package unit

30 capsules/bottle, 500 capsules/bottle