F.D. Caine 1:100,000 Injection

Adult administration

For conduction anesthesia or infiltration anesthesia, use 0.3 to 2 mL (6 to 40 mg as lidocaine hydrochloride).

This medication is an amide-type local anesthetic and should not be used in certain patients. Particularly, patients who have had allergic reactions to this medication or other amide-type local anesthetics, those allergic to vasoconstrictors, and patients with conditions such as hypertension, atherosclerosis, heart failure, hyperthyroidism, diabetes, and vascular spasms should not be administered this drug. Additionally, careful administration is needed in patients using halogen-containing inhalational anesthetics such as halothane or those taking tricyclic antidepressants or MAO inhibitors. This medication contains sodium metabisulfite, which may cause allergic reactions or asthma attacks in susceptible individuals, especially in patients with asthma. During administration, adverse reactions such as shock symptoms, hypotension, pulse irregularities, and respiratory depression may occur, so careful monitoring of the patient is necessary. If these abnormal symptoms arise, administration should be immediately discontinued and appropriate treatment should be provided. There is also a rare risk of a severe side effect called malignant hyperthermia, so if symptoms such as sudden temperature rise or muscle rigidity occur, drug administration must be stopped immediately, and specialized treatment is required. Central nervous system disturbances may present as tremors, seizures, drowsiness, anxiety, dizziness, and nausea, which should be closely monitored. Allergic reactions such as skin rash, swelling, and difficulty breathing may also occur, and any abnormal symptoms should be reported to medical personnel immediately. When using this drug, it is important to be prepared to perform first aid promptly in case of shock or toxicity. As much as possible, use the lowest concentration and the minimum effective dose; administer only a small amount slowly in highly vascular areas to prevent rapid absorption. When injecting, care should be taken to avoid the needle entering a blood vessel, and the patient's overall condition should be thoroughly checked. Women who are pregnant or may become pregnant should use this drug only when the benefits outweigh the risks, as its safety has not been established. The components of this drug may be excreted in small amounts in breast milk, but the effects on nursing infants are not clearly known, so use should be discussed with medical personnel beforehand. Elderly patients may be more sensitive to the epinephrine contained in this medication, so their condition should be monitored closely when administered. Particularly in cases of epidural anesthesia, the anesthetic coverage may expand in elderly patients, so the dosage should be adjusted with caution. Lastly, this drug should not be used for ophthalmic purposes.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor
• Malignant hyperthermia, shock, facial pallor, pulse irregularities, respiratory depression
• Asthma attack
• Anaphylaxis
• Severe allergic reactions

Mild side effects

• Drowsiness
• anxiety
• excitement
• neglect
• dizziness
• nausea
• vomiting
• tremors
• seizures
• tachycardia

This medication may be sensitive to light, so it should be stored in a tightly sealed container that is protected from light. It is important to maintain room temperature between 10 degrees and 30 degrees Celsius. Proper storage will help preserve the efficacy of the drug for a longer period.

Appearance

Colorless, transparent liquid in a cartridge-type ampoule

Package unit

50 ampoules/box [1.8 mL/ampoule x 50]