Septanest Injection 1/200,000

Adult administration

Administer via local injection or infiltrative injection into the oral mucosa. An aspiration test must be performed to ensure that it is not injected into blood vessels. The injection speed should not exceed 1 mL per minute. The recommended dosage used in general procedures is listed in the table below. The maximum dose for healthy adults weighing over 70 kg should not exceed 500 mg of articaine hydrochloride. Recommended dosages (for example): - Infiltration:

Child administration

For children over 4 years, the dosage is determined according to age, weight, and type of procedure. The minimum dose should be used, and for children aged 4 (or weighing 20 kg or more) and older, the maximum dose of articaine hydrochloride should not exceed 5 mg per kg of body weight.

This medication should be administered carefully to avoid accidental injection into the bloodstream. Injection into blood vessels can result in the rapid spread of the drug throughout the body, leading to serious side effects. Patients with hypertension or diabetes should use this drug cautiously as there may be a risk of tissue necrosis in the localized area. Patients with allergies to this drug or its components, certain heart diseases, liver diseases, kidney diseases, epilepsy, children under 4 years old, etc., should not use this drug. Patients taking anticoagulants or antiplatelet drugs may have an increased risk of bleeding and should be monitored. Patients with cardiovascular diseases may be affected in heart function due to the epinephrine component present in this drug, thus requiring strict observation by healthcare professionals. Patients with a history of stroke are advised to postpone treatment due to the risk of recurrence. Patients with impaired liver or kidney function, elderly patients, and those with uncontrolled diabetes should have their dosage adjusted and be closely monitored. Patients with asthma or sensitivity to sulfites should be cautious as they may experience allergic reactions or worsening asthma. This drug can interact with various medications, so patients should inform their healthcare provider about any medications they are taking. Use only when necessary during pregnancy and with caution during breastfeeding. After receiving this drug, dizziness or visual disturbances may occur, so caution is needed when driving or operating machinery. In case of overdose, serious side effects related to the nervous system, respiratory system, and cardiovascular system may occur, necessitating immediate medical attention. Before use, it is essential to check the patient's allergy history and past medical history, and avoid administration if there is an infection at the injection site. After use, it is advisable to refrain from eating until sensation returns to normal at the injection site. This drug requires that aspiration tests be carefully performed to ensure that the injection needle does not enter a blood vessel, and any unusual symptoms should be monitored while communicating continuously with the patient. Once opened, the cartridge should not be reused, and it must not be mixed with other drugs.

Serious side effects

Urticaria, severe swelling, angioedema (facial, tongue, lips, throat, larynx, periorbital edema), chest tightness, difficulty breathing, anaphylaxis, anaphylactoid reactions, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, bronchospasm, asthma, respiratory distress, jaundice (yellowing of the skin or eyes), profound lethargy, sudden and extremely severe headaches, thunderclap headache, seizures

Mild side effects

Gingivitis, nervousness, anxiety, euphoria, neuralgia, sensory loss, numbness, sensory hyperesthesia, dysesthesia, taste disturbance, loss of taste, discomfort, temperature sensory hyperesthesia, headache, burning sensation, drowsiness, nystagmus, sensory disturbances after mandibular or inferior alveolar nerve blocks, restlessness, anxiety, tremor, speech impairment, double vision, visual disturbances, ptosis, miosis, exophthalmos, auditory hyperesthesia, tinnitus, bradycardia, tachycardia, palpitations, hypotension, hypertension

This drug should be stored in a sealed container to prevent air ingress, and it should be kept at room temperature between 1 and 25 degrees Celsius. It is also important to store it in a dark place to avoid exposure to light.

Appearance

A cartridge-type ampoule filled with a colorless, transparent liquid

Package unit

1.7 mL x 50 cartridges