Medication info

Asacol Suppository 500 mg (Mesalazine)

Prescription medicationExternal use
Ingredient · strength
Mesalazine›500mg
Manufacturer / importer
Daewoong Pharmaceuticals
Appearance
Grayish-brown, spindle-shaped suppository
Packaging
20 pieces (5 pieces/strip) X 4
Approval status
Active

MFDS item code 200307870 · Notified 2003.11.21 · Insurance code 641601850

Summary

Main use
Treatment of acute exacerbations of ulcerative colitis (including proctitis) and prevention of recurrence
Who uses it
Adults
Adult use
Treatment of acute attacks of mild to moderate ulcerative colitis: The usual dose for adults is one unit (500mg) inserted rectally three times daily. Long-term maintenance therapy and prevention of recurrence: The usual dose for adults is one unit (500mg) inserted rectally twice daily.

Ingredients

Importer
Daewoong Pharmaceuticals

Efficacy & effects

Treatment of acute exacerbations of ulcerative colitis (including proctitis) and prevention of recurrence

  • Mild ulcerative colitis
  • moderate ulcerative colitis
  • proctitis
  • distal rectal S-shaped colonitis
View approved original text

This medication is used to treat acute attacks of mild to moderate ulcerative colitis, especially proctitis and distal rectal S-shaped colonitis occurring within 20 cm of the anus, and to prevent recurrence.

How to use

Adult use

Treatment of acute attacks of mild to moderate ulcerative colitis: The usual dose for adults is one unit (500mg) inserted rectally three times daily. Long-term maintenance therapy and prevention of recurrence: The usual dose for adults is one unit (500mg) inserted rectally twice daily.

Precautions

This medication should not be used in patients with an allergy to salicylic acid or salicylates. Patients with severe liver or kidney disorders should also avoid this medication. Patients with peptic ulcers or coagulation disorders should refrain from this medication. Newborns or premature infants under 4 weeks should particularly avoid using this medication in suppository form. Patients with bronchial asthma or other drug allergies should use this medication with caution. Patients with liver or kidney issues and blood disorders also require careful attention. Women who are pregnant or breastfeeding, children aged between 2 and under 15, and elderly patients should also exercise caution when using this medication. While using this medication, side effects such as diarrhea, vomiting, headache, abdominal pain, or rash may occur, so symptoms should be closely monitored. Rarely, severe side effects such as myocarditis, hepatitis, pancreatitis, and severe skin reactions may occur, so any unusual symptoms should be reported to a doctor immediately. Regular blood tests, liver function tests, and kidney function tests should be performed before treatment and for a certain period afterward, and immediate testing should be done if any warning signs arise. This medication may interact with other drugs, so inform your doctor or pharmacist if you are taking any other medications. During pregnancy or breastfeeding, this medication should only be taken cautiously when necessary, and if diarrhea occurs while breastfeeding, breastfeeding should be discontinued. Elderly patients may have reduced kidney function, so they should be especially careful and have regular blood tests. In case of overdose, inducing vomiting or gastric lavage may be performed, and treatment to correct fluid and electrolyte imbalances may be necessary. This medication should be stored out of reach of children and should not be transferred to another container.

Side effects

Diarrhea, nausea, abdominal pain, headache, vomiting, rash, hypersensitivity reactions, drug-induced hyperthermia, Stevens-Johnson syndrome, toxic epidermal necrolysis, itching, discomfort in the rectum, inability to hold back stool, anemia, aplastic anemia, agranulocytosis, neutropenia, leukopenia, pancytopenia, thrombocytopenia, eosinophilia, anaphylactic reaction, eosinophilia, drug reaction with eosinophilia and systemic symptoms (DRESS), dizziness, peripheral neuropathy, idiopathic intracranial hypertension, myocarditis, pericarditis, shortness of breath, cough, bronchospasm, allergic alveolitis, pulmonary eosinophilia, interstitial lung disease, pulmonary infiltrates, pneumonia, pleuritis, nausea, abdominal distension, belching, increased amylase, acute pancreatitis, colitis, increased aminotransferases, elevated cholestasis parameters, hepatotoxicity, hepatitis, cholestatic hepatitis, cirrhosis, liver failure, urticaria, erythematous rash, photosensitivity, hair loss, allergic rash, erythema multiforme, myalgia, arthralgia, erythema nodosum syndrome, abnormal kidney function, acute interstitial nephritis, chronic interstitial nephritis, nephrotic syndrome, renal failure, urine discoloration, nephrolithiasis, reversible oligospermia, hyperthermia, abdominal bloating, burping, elevated methemoglobin levels, conjunctivitis, youth benign intracranial hypertension, angioedema

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is important to keep the storage temperature below 25 degrees Celsius. This will help maintain the medication's effectiveness for a longer period.

Appearance and packaging

Appearance

Grayish-brown, spindle-shaped suppository

Package unit

20 pieces (5 pieces/strip) X 4

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.