Loxlprofen Sodium Hydrate Tablets

Adult dose

1. For indications 1 and 2: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For single-dose therapy, administer 60-120 mg orally. 2. For indication 3: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally. In principle, it can be administered twice a day, up to a maximum of 180 mg daily. It is advisable to avoid taking it on an empty stomach.

This medication increases the risk of gastrointestinal bleeding for those who regularly consume more than three glasses of alcohol daily; therefore, it is essential to consult a physician or pharmacist. This medication may increase the risk of cardiovascular disease, so those with a history of heart disease, stroke, or risk factors should be more cautious. Severe gastrointestinal side effects such as gastrointestinal bleeding, ulcers, and perforations may occur; therefore, elderly patients or those with a history of gastrointestinal diseases should use it with caution. Patients with peptic ulcers, severe liver failure, kidney failure, heart failure, or hypersensitivity to this drug or similar medications should not take it. Patients with a history of asthma or allergic reactions or certain inflammatory bowel diseases should also avoid using this medication. For prolonged use of this medication, regular blood tests and liver and kidney function tests should be conducted to monitor for abnormalities. If symptoms such as rash, itching, difficulty breathing, or decreased blood pressure occur during use, stop taking the medication immediately and inform the healthcare provider. If gastrointestinal symptoms such as abdominal pain, vomiting, bloody stools, or chest burning sensation appear, immediate treatment is required, and medication should be discontinued if symptoms are severe. This medication may cause side effects like drowsiness, dizziness, and headaches, so caution is needed when driving or operating machinery. Taking this medication with other non-steroidal anti-inflammatory drugs may increase the risk of side effects, so it is advisable not to combine them. There may be interactions with certain blood pressure medications, diuretics, anticoagulants, lithium, methotrexate, etc., so inform the healthcare provider of any medications being taken. It should not be taken during the late stages of pregnancy as it may pose risks to the fetus; during the early to mid-pregnancy stages, it should only be used cautiously at the minimum effective dose as determined by a physician. It is safest for breastfeeding women to avoid using this medication. Safety in children has not been established, so it is advisable not to use it in pediatric patients. Elderly patients have a greater risk of side effects, so extreme caution is needed when prescribing. This medication should be stored out of the reach of children, and it is advisable not to transfer it to other containers as this may compromise quality and safety.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling of the skin, pain in mucous membranes of the mouth/eyes, wheezing or difficulty breathing, asthma attack, cough with fever combined respiratory distress, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Occasionally rash
• itching
• fever
• abdominal pain
• discomfort in the stomach area
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. Proper storage will safely preserve the medication's efficacy.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle