Asolofen Tablets (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2, ○ Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For a single treatment, 60–120 mg should be administered orally. 2. For indications 3, ○ Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally. In principle, it can be taken twice a day, with a maximum total of 180 mg per day. On an empty stomach,

This medication may cause gastric bleeding in individuals who regularly consume more than three glasses of alcohol daily, so it is essential to consult a doctor or pharmacist. This medication poses a risk of cardiovascular issues and may increase the likelihood of heart disease or stroke, so those with cardiovascular conditions or risk factors should take particular caution. Severe gastrointestinal issues such as gastrointestinal bleeding, ulcers, or perforations may occur. Therefore, individuals with gastrointestinal problems or elderly patients should carefully monitor gastrointestinal symptoms while taking this medication. Individuals with peptic ulcers, serious blood disorders, liver dysfunction, kidney dysfunction, or heart failure should not take this medication, and those allergic to non-steroidal anti-inflammatory drugs, including aspirin, should also avoid it. Those with a history of peptic ulcers or blood disorders, liver dysfunction, kidney dysfunction, or heart failure should follow their doctor's instructions with extra caution when using this medication. If symptoms of hypersensitivity such as skin rash, hives, shortness of breath, or low blood pressure occur, use should be immediately discontinued and medical consultation sought. If gastrointestinal symptoms such as abdominal pain, nausea, vomiting, or bloody stools arise, use should be immediately stopped and treatment should be sought. This medication may cause drowsiness, dizziness, or headaches, so caution is advised when driving or operating machinery. Liver or kidney function may be adversely affected; therefore, regular blood tests and liver and kidney function tests should be conducted during prolonged use. Taking this medication in combination with other non-steroidal anti-inflammatory drugs can increase the risk of side effects, so it is recommended not to combine them. Interactions may occur with certain blood pressure medications, anticoagulants, antibiotics, lithium, methotrexate, so patients should inform their doctor about any medications they are taking. It should not be taken during late pregnancy as it may pose a risk to the fetus, and caution should also be exercised during early or mid-pregnancy. This medication is not recommended for breastfeeding individuals. Safety for children has not been established, so it is advisable not to use it in children. Elderly patients are at a higher risk of side effects, so caution is needed when taking this medication. This medication should be kept out of the reach of children and should not be transferred to other containers for safety.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, shock, anaphylaxis-like symptoms, peptic ulcer, perforation, hematemesis, melena, bloody stools, shock, intestinal perforation, severe headache, confusion, visual disturbances, paralysis, jaundice (yellowing of the skin or eyes), fulminant hepatitis, liver dysfunction, acute renal failure, difficulty breathing, asthma attack, interstitial pneumonia, skin and mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis.

Mild side effects

• Occasionally
• symptoms such as rash
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea

This medication should be stored in a tightly sealed container to prevent air ingress, at room temperature between 1 degree and 30 degrees. Storing it this way helps maintain the effectiveness of the medication.

Appearance

White round tablets

Package unit

30 tablets/bottle, 500 tablets/bottle