Coxibcapsule (Meloxicam)

Adult dose

1. Acute exacerbations of osteoarthritis (degenerative arthritis): ○ Adults: Administer 7.5 mg of meloxicam orally once daily. If symptoms do not improve, the dose may be increased to up to 15 mg daily as needed. 2. Rheumatoid arthritis, ankylosing spondylitis: ○ Adults: Administer 15 mg of this drug orally once daily. The dose may be reduced to 7.5 mg daily according to the response to treatment. This drug should not be administered at doses exceeding 15 mg daily and should be taken with water or another beverage during a meal. ○ In elderly patients or those at increased risk of adverse reactions, treatment is usually initiated at a dose of 7.5 mg daily. ○ Patients with severe renal impairment undergoing hemodialysis should not receive more than 7.5 mg daily.

This medication may cause gastrointestinal bleeding if taken by individuals who regularly consume more than three glasses of alcohol a day, so consultation with a doctor or pharmacist is essential. This medication can influence the cardiovascular system, increasing the risk of thrombosis, myocardial infarction, and stroke; therefore, patients with cardiovascular diseases or risk factors must be monitored closely. Serious adverse reactions such as gastrointestinal bleeding, ulcers, and perforation may occur, particularly in elderly patients or those with a history of gastrointestinal diseases, who should be especially cautious and seek treatment immediately if symptoms arise. This medication may rarely cause serious allergic reactions or dermatitis; if skin rashes or mucosal damage occur, discontinuation of use should be immediate. It can affect kidney function, so patients with kidney diseases or those taking diuretics should have their renal function monitored periodically. Liver dysfunction may occur, thus patients with liver diseases should undergo regular liver function tests and discontinue use if abnormal symptoms develop. This medication should not be used during pregnancy as it may harm the fetus, and breastfeeding women should also avoid taking it. This medication may affect blood coagulation, increasing the risk of bleeding, so patients taking anticoagulants or antiplatelet agents need to exercise caution. Co-administration with other non-steroidal anti-inflammatory drugs or aspirin can increase the risk of gastrointestinal bleeding and cardiovascular side effects, so it is advisable to avoid such combinations. Elderly patients, having compromised renal, liver, and cardiac functions, face a higher risk of adverse reactions and should use the minimal effective dose cautiously. During treatment with this medication, symptoms such as drowsiness, dizziness, and visual disturbances may occur, thus caution is required when driving or operating machinery. In case of overdose, symptoms such as vomiting, drowsiness, gastrointestinal bleeding, and renal and liver dysfunction may occur, necessitating immediate medical attention, as there is no specific antidote and supportive therapy may be required.

• Gastrointestinal bleeding
• cardiovascular thrombotic reaction
• myocardial infarction
• stroke
• gastrointestinal or intestinal bleeding
• ulcer
• perforation
• exfoliative dermatitis
• mucocutaneous syndrome
• toxic epidermal necrolysis

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it is important to store it at room temperature between 1 degree and 30 degrees Celsius to maintain its effectiveness.

Appearance

Hard capsules with a greenish color filled with yellow powder.

Package unit

30 capsules/bottle, 300 capsules/bottle