Crotal Tablet (Aceclofenac)

Adult dose

As Aceclofenac, take 100 mg twice a day every 12 hours. Do not chew or crush the tablet; swallow it whole. Adjust the dosage as appropriate according to the symptoms. To minimize the risk of cardiovascular adverse effects, it should be administered at the lowest effective dose for the shortest duration.

People who regularly consume more than three alcoholic drinks a day should consult a doctor or pharmacist before taking this medication, as taking it with alcohol may increase the risk of gastrointestinal bleeding. This drug may increase the risk of cardiovascular diseases and cerebrovascular diseases. Patients with cardiovascular risk factors such as heart failure, hypertension, diabetes, and smoking should use this drug with caution. The dose and duration should be minimized, and treatment effects and side effects should be monitored regularly. Additionally, this drug can cause serious gastrointestinal side effects such as gastrointestinal bleeding, ulcers, and perforation. Elderly patients or those with a history of gastrointestinal diseases should be particularly cautious and seek immediate medical attention if any unusual symptoms occur. Patients with active peptic ulcers or bleeding, those allergic to this drug or similar medications, pregnant women in late pregnancy, nursing mothers, and patients with severe renal or liver dysfunction should not use this drug. Patients with renal or liver insufficiency, the elderly, heart failure patients, and hypertension patients should be particularly cautious when using this medication and should have their condition regularly assessed under medical supervision. This drug may cause various side effects, including dizziness, skin rashes, gastrointestinal disorders, and abnormal liver function, so symptoms should be discussed with healthcare professionals immediately. Moreover, this drug may interact with other medications, especially when taken with anticoagulants, diuretics, ACE inhibitors, and antidiabetic agents; it is advisable to consult a doctor. This drug should not be used during late pregnancy as it may harm the fetus; women who are pregnant or planning to become pregnant should consult a doctor before taking this medication. Nursing mothers should also discuss the need to discontinue breastfeeding when taking this drug. Safety and efficacy in children and adolescents have not been established, and it is not recommended. Elderly patients have a higher risk of gastrointestinal bleeding and perforation, so special caution is necessary when taking this medication. In case of overdose, symptoms such as gastrointestinal irritation, hypotension, respiratory depression, and seizures can occur, requiring immediate medical attention.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, anaphylactic reaction, shock, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, mucocutaneous syndrome), hypertension, heart failure, congestive heart failure, cardiovascular thromboembolic events, myocardial infarction, stroke, gastrointestinal bleeding, gastrointestinal ulcer, perforation, significant reduction in urine output, severe generalized edema, liver abnormalities (jaundice), acute coronary syndrome, severe renal

Mild side effects

• Dizziness
• abnormal liver enzyme levels
• itching
• rash
• anemia
• leukopenia
• thrombocytopenia
• neutropenia
• hemolytic anemia
• aplastic anemia

This medication should be stored in a sealed container to protect from air and moisture. It is recommended to maintain storage temperatures between 1°C and 30°C in room temperature.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle