Pepsiride Tablet (Levosulpiride)

Adult dose

Adults: Administer 25 mg of levosulpiride orally per dose, 3 times daily before meals.

This medication must not be used by women who are pregnant or may become pregnant, nor by nursing mothers. It should also not be administered to patients with gastrointestinal bleeding, mechanical obstructions, or perforations. Particularly, patients with a tumor known as pheochromocytoma should avoid this medication due to the risk of worsening hypertension. Patients with any allergic reactions to this drug or who cannot tolerate it should also refrain from using it. It is safer not to administer this to patients with epilepsy, manic episodes, or in the manic phase of bipolar disorder. Additionally, caution is necessary for patients with malignant mammary diseases, as this medication may exacerbate breast-related symptoms. This drug contains lactose, thus it should not be given to patients with lactose intolerance or specific genetic metabolic disorders. Hypertensive patients, children, and the elderly should use this medication cautiously. In particular, symptoms of extrapyramidal side effects can easily appear in children, so overdoses should be avoided. While taking this medication, careful observation is required for any endocrine-related symptoms such as amenorrhea, galactorrhea, and gynecomastia, as these may occur. Rarely, extrapyramidal symptoms such as tremors, tongue twisting, and agitation may occur, and if any appear, use should be discontinued immediately. With long-term use, involuntary movements around the mouth may persist, so caution is needed. In the gastrointestinal system, symptoms like dry mouth, heartburn, nausea, vomiting, diarrhea, and constipation may occur. In the cardiovascular system, hypertension or arrhythmia may emerge. Additionally, a serious side effect known as neuroleptic malignant syndrome has been reported; immediate treatment should be sought if symptoms such as high fever, muscle rigidity, or altered consciousness appear. It is advisable to avoid driving or operating machinery that requires focus while taking this medication. In cases of high dosage, irregular heartbeats may occur, so special caution is required for the elderly or those at risk for stroke. Caution should also be taken when coadministering with other medications, particularly anticholinergics, narcotic analgesics, digitalis preparations, and other benzamide drugs, as side effects may increase. Alcohol should also be avoided. Pregnant or nursing women should avoid this medication as it may pose risks to the fetus or newborn. The elderly may experience decreased renal function, leading to prolonged retention of the medication in the body, necessitating dosage adjustment and monitoring for adverse reactions. Finally, this medication has an antiemetic effect and may mask vomiting caused by other factors, therefore it should be used cautiously while monitoring symptom changes.

• Amenorrhea
• galactorrhea
• gynecomastia
• tremors
• tongue twisting
• agitation
• involuntary movements around the mouth
• thirst
• heartburn
• nausea

This medication should be stored in a tightly closed container to protect it from air and moisture, and should ideally be kept at a temperature between 1 to 30 degrees Celsius at room temperature. Proper storage can help maintain the medication's efficacy over time.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle