Roxet Slow Release Capsule 75 mg (Roxatidine Acetate Hydrochloride Slow Release Granule 45.45%)

Adult dose

Adults: 1) Gastric or duodenal ulcer, reflux esophagitis, Zollinger-Ellison syndrome: Administer 75mg of roxatidine acetate hydrochloride per dose orally twice daily, after breakfast and dinner. For gastric or duodenal ulcers, 150mg per dose may also be administered once daily in the evening. Gastric and duodenal ulcers are usually treated within 4 weeks, but symptoms resolve within a few days. If the ulcer has not healed after 4 weeks of treatment, continue the same dose for an additional 2 weeks. For patients with impaired renal function and a creatinine clearance of approximately 20～50mL/min, administer 75mg per dose once daily in the evening. For patients with a creatinine clearance of 20mL/min or less, administer 75mg per dose every 2 days in the evening. 2) Acute gastritis or acute exacerbation of chronic gastritis: Administer 75mg per dose once daily after the evening meal or at bedtime. 3) Pre-anesthetic administration: Administer 75mg per dose twice (at bedtime on the day before surgery and 2 hours before induction of anesthesia on the day of surgery). Adjust the dose as appropriate according to age and symptoms.

This medication should not be used in patients who are allergic to this drug or any of its components. Patients with impaired liver function or decreased kidney function may experience increased drug concentration; hence caution must be taken by adjusting the dosage or prolonging the administration interval. Care should be taken when using in elderly patients or those who have experienced hypersensitivity reactions to medications. This medication contains the dye yellow No. 4, so patients with a history of allergy to this ingredient should be particularly cautious. When using this medication, hypersensitivity reactions such as shock symptoms, skin rashes, and itching may occur; if any unusual symptoms arise, use should be immediately discontinued and the hospital notified. Regular blood tests should be performed, as results may change; if abnormal signs occur, administration should be stopped. Symptoms indicating liver function abnormalities, gastrointestinal symptoms, or neurological symptoms may occur, so careful monitoring is necessary. If severe skin reactions occur, the medication should be discontinued immediately, and appropriate treatment sought. Rarely, muscle-related side effects may occur; if muscle pain or increased related enzyme levels are noted, consult a doctor immediately. This drug may interact with other medications, especially caution is advised when taking ketoconazole or midazolam. Women who are pregnant or may become pregnant should thoroughly consider the benefits and risks of using this medication. Breastfeeding women should avoid breastfeeding while taking this medication as it may be transmitted through breast milk. It is recommended not to use this drug in children under 14 years of age as its safety has not been established. Elderly patients may require dosage adjustments due to increased drug concentration from decreased kidney function. This medication should be stored out of reach of children, and it is advisable to avoid transferring it to other containers.

shock

This medication must be stored in a tightly sealed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature. Proper storage will help maintain the efficacy of the medication.

Appearance

A capsule with a green upper part and white lower part containing white slow-release granules.

Package unit

30 capsules/bottle, 100 capsules/bottle