Apen Tablet (Aceclofenac)

Adult dose

For adults, 100 mg of aceclofenac is taken twice a day every 12 hours. In patients with hepatic impairment, the initial dose is 100 mg per day. This medication should be swallowed whole without chewing or crushing. Adjustments may be made according to symptoms. To minimize cardiovascular adverse reactions, it should be taken at the lowest effective dose for the shortest duration necessary.

This medication may pose a risk of gastrointestinal bleeding in individuals who regularly consume more than three drinks of alcohol a day, so it is essential to consult a physician or pharmacist. This medication can increase the risk of cardiovascular and cerebrovascular diseases, hence patients with heart failure or risk factors for cardiovascular diseases should use it cautiously, taking the lowest effective dose for the shortest duration possible. Patients with a history of ulcers or gastrointestinal bleeding may experience severe gastrointestinal bleeding or perforation when taking this medication, so it should not be administered. Elderly patients are particularly at higher risk for gastrointestinal bleeding and perforation, and caution should be exercised when prescribing to them. Patients with a history of asthma or allergic reactions may exhibit hypersensitivity to this medication, so they must take precautions before use. It is safest for pregnant women in the late stages or nursing mothers not to take this medication, and women in the early to mid-pregnancy should also use it cautiously. Patients with renal or hepatic impairment, heart failure, hypertension, etc., require special attention while taking this medication, and regular monitoring may be necessary. If any unusual symptoms such as dizziness, skin rash, or difficulty breathing appear during treatment, immediate consultation with healthcare professionals is essential. Interactions may occur when taken with other medications; therefore, if other medications are being taken, it is crucial to consult a physician or pharmacist. Caution may be required while driving or operating hazardous machinery, and it is advisable to avoid such activities during treatment. It is recommended not to use this medication in children or adolescents as safety and efficacy are not established.

Serious side effects

• Hives
• severe swelling (edema)
• anaphylactic reaction
• shock
• difficulty breathing
• asthma attack
• skin desquamation
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• severe rash with high fever

Mild side effects

• Dizziness
• abnormal liver enzyme levels
• itching
• rash
• anemia
• leukopenia
• thrombocytopenia
• neutropenia
• hemolytic anemia
• aplastic anemia

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It should be kept at room temperature between 1 degree and 30 degrees.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle