Euglex Tablet 2 mg (Glymepiride)

Adult dose

This medication is taken orally once a day. It should be taken before breakfast or right before the first meal. The dosing starts with 1 mg of glymepiride once daily. If needed, the dose can be increased by 1 mg every 1-2 weeks. Generally, when doses above 4 mg are given, additional effects are minimal, although some patients may need to increase the dosage to 6 mg or 8 mg. If 4 mg once daily fails, switching to insulin therapy should be considered; otherwise, combination therapy with insulin or other oral hypoglycemic agents may be necessary.

This medication should not be used in patients with insulin-dependent diabetes or those experiencing diabetic ketoacidosis or coma. Additionally, patients who have had allergic reactions to this drug or its components should not be administered this medication. The safety and efficacy of this drug have not been established in patients with very poor liver or kidney function, and insulin treatment is recommended in such cases. Women who are pregnant or likely to become pregnant, as well as nursing mothers, should not take this medication. Patients with severe infections, those undergoing surgery, or those with significant trauma may require insulin treatment, so caution should be exercised before using this drug. Patients with gastrointestinal disorders such as diarrhea or vomiting may have inadequate drug absorption, increasing the risk of hypoglycemia. This drug contains lactose; therefore, patients with lactose intolerance or genetic lactose metabolism disorders should avoid using it. During the first week of taking this medication, close monitoring of blood glucose levels is essential due to an increased risk of hypoglycemia, particularly in elderly patients, those with irregular eating patterns, those in poor nutritional condition, heavy alcohol consumers, and individuals with compromised kidney or liver function. Also, caution is necessary in patients with other endocrine disorders or those who have overdosed on medications. If hypoglycemic symptoms occur while taking this drug, the patient should promptly inform a doctor or pharmacist, as dosage adjustments may be necessary. This medication can lower blood sugar, so hypoglycemia may occur. Symptoms of hypoglycemia may include headache, severe hunger, nausea, fatigue, confusion, dizziness, drowsiness, and altered consciousness; in severe cases, it may lead to coma, necessitating immediate treatment. Additionally, initial use may result in blurred vision, gastrointestinal disturbances, liver function abnormalities, blood disorders, and allergic reactions, so any unusual symptoms should be reported to medical personnel immediately. This medication should be taken regularly to control blood sugar, and it is important to adhere to dietary and exercise regimens. If hypoglycemia occurs, consuming food containing sugar can quickly alleviate symptoms, so it is advisable to always carry a source of sugar. Regular blood sugar and urine tests should be conducted while on this medication, and dose adjustments may be necessary based on the patient's condition, as directed by a physician. This medication may interact with other drugs, so patients must inform healthcare providers of any other medications they are taking. In particular, some antibiotics, antifungals, antihypertensives, steroids, and alcohol may affect blood sugar control when taken concomitantly. In case of overdose, severe hypoglycemia may occur, so immediate emergency treatment is required, and intravenous glucose administration may be necessary at a hospital. The safety of this medication has not been confirmed in children, and particular caution is required in elderly patients who may have reduced kidney function when selecting a dose. Finally, this medication should be stored out of the reach of children, and it is safest to keep it in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash accompanied by fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, breathlessness or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggressiveness
• decreased concentration
• reduced alertness or reaction time

This medication is sensitive to air and moisture, so it must be stored in a tightly closed container. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Green rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 30 tablets (10 tablets/PTP) × 3