Medication info
Lexofan Tablets (Loxoprofen Sodium)

Lexofan Tablets (Loxoprofen Sodium)

Prescription medicationTablet경구
Ingredient · strength
Loxoprofen Sodium›68.1mg / 1 tablet
Manufacturer / importer
한국휴텍스제약(주)
Appearance
White round tablets
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 200300064 · Notified 2003.12.13 · Insurance code 649100180

Summary

Main use
Relief of inflammation and pain associated with chronic rheumatoid arthritis, relief of postoperative pain, antipyretic and analgesic effects for acute upper respiratory tract infection
Who takes it
Adults
Adult dose
1. For indications 1 and 2 - Administer 60 mg orally three times a day. - For a single-dose therapy, administer 60-120 mg orally. 2. For indication 3 - Administer 60 mg orally. - In principle, can be administered twice daily, with a maximum of 180 mg per day. - It is advisable to avoid taking it on an empty stomach. - Adjust the dosage appropriately according to symptoms.

Ingredients

Manufacturer
한국휴텍스제약(주)

Efficacy & effects

Relief of inflammation and pain associated with chronic rheumatoid arthritis, relief of postoperative pain, antipyretic and analgesic effects for acute upper respiratory tract infection

  • Chronic rheumatoid arthritis
  • osteoarthritis
  • low back pain
  • adhesive capsulitis
  • frozen shoulder syndrome
  • postoperative pain
  • post-traumatic pain
  • post-extraction pain
  • acute upper respiratory infection
  • acute bronchitis
View approved original text

This medication is effective in relieving pain and inflammation caused by various inflammatory diseases such as chronic rheumatoid arthritis, osteoarthritis, low back pain, adhesive capsulitis, and frozen shoulder syndrome. It is also used to reduce inflammation and pain that may occur after surgery, trauma, or tooth extraction. It helps reduce fever and alleviate pain during upper respiratory infections accompanied by acute upper respiratory inflammation and acute bronchitis. This drug is mainly used to suppress inflammation and relieve fever and pain, thereby improving the patient's discomfort.

How to take

Adult dose

1. For indications 1 and 2 - Administer 60 mg orally three times a day. - For a single-dose therapy, administer 60-120 mg orally. 2. For indication 3 - Administer 60 mg orally. - In principle, can be administered twice daily, with a maximum of 180 mg per day. - It is advisable to avoid taking it on an empty stomach. - Adjust the dosage appropriately according to symptoms.

Precautions

This drug may cause gastric bleeding in individuals who regularly consume more than three alcoholic beverages daily; therefore, consultation with a doctor or pharmacist is essential. This drug can increase the risk of cardiovascular diseases, so patients with a history of cardiovascular disease or risk factors should exercise particular caution and monitor for cardiovascular symptoms during use. This drug may cause serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforation, so elderly patients and those with a history of gastrointestinal disease should use it with extra caution. Patients with a history of peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, or heart failure, and those allergic to this drug or its components should not take it. Pregnant women in the late stages of pregnancy, nursing mothers, patients with inflammatory bowel disease, and those who are lactose intolerant should also avoid this medication. Patients with a history of peptic ulcers or blood, liver, or kidney diseases, elderly patients, and those with hypertension should be administered this drug with caution and closely monitor for adverse reactions during administration. This drug may cause allergic reactions such as rash, itching, hives, and in severe cases may lead to emergencies such as shock or anaphylaxis, so discontinuation should occur immediately if such symptoms appear. Gastrointestinal adverse reactions may include abdominal pain, nausea, vomiting, and bloody stools, and if these symptoms occur, medical personnel should be informed immediately. Neurological symptoms such as drowsiness, dizziness, and headache may occur, so caution is required when driving or operating machinery. Liver function impairment or kidney function abnormalities may occur; therefore, regular tests and observations are necessary during prolonged use. It is advised not to take this drug concurrently with other non-steroidal anti-inflammatory drugs, and it may interact with specific medications, so it is vital to inform your doctor of any medications being taken. In early and mid-pregnancy, it should be administered at the minimum dose only when necessary, and it should never be taken in the late stages of pregnancy. Nursing mothers are recommended not to take this drug. Safety in children has not been established, so it should be administered cautiously to children. Elderly individuals are at higher risk for adverse reactions, so caution is needed during administration, and it should be stored out of reach of children and not transferred to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (including angioedema, facial swelling), tightness in the chest, difficulty breathing, shock, symptoms resembling anaphylaxis, severe rash with high fever, skin peeling, pain in oral/ocular mucosa, peptic ulcer, gastrointestinal bleeding, perforation, hematemesis, melena, bloody stools, intestinal perforation, liver dysfunction (including jaundice), fulminant hepatitis, acute renal failure, nephrotic syndrome, interstitial nephritis, respiratory distress, asthma attacks, interstitial pneumonia, skin nodules

Mild side effects

  • Itching
  • fever
  • abdominal pain
  • discomfort in the upper abdomen
  • loss of appetite
  • nausea
  • vomiting
  • diarrhea
  • constipation
  • chest tightness
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  • indigestion
  • stomatitis
  • dryness of the mouth
  • abdominal bloating
  • drowsiness
  • numbness
  • dizziness
  • headache
  • anemia
  • eosinophilia
  • hematuria
  • proteinuria
  • edema
  • chest pain
  • anxiety
  • fatigue
  • palpitations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is recommended to maintain the storage temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and safety.

Appearance and packaging

Appearance

White round tablets

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.