Simvastatin Tablets 40 mg (Simvastatin)

Adult dose

To reduce the risk of cardiovascular disease, the recommended initial starting dose is 40 mg once daily. For treatment of hyperlipidemia, the general initial starting dose is 20 mg once daily in the evening, and patients with mild to moderate hypercholesterolemia may start at 10 mg. Administer 5 mg to 40 mg once daily in the evening, adjusting the dose before administration based on pre-treatment LDL-cholesterol level, treatment goals, and the patient's response to the medication.

Child dose

The recommended initial dose for pediatric patients (aged 10 to 17 years) with heterozygous familial hypercholesterolemia is 10 mg once daily in the evening. The recommended dosage range is 10 mg to 40 mg once daily, with the recommended maximum dose being 1

This drug may cause serious side effects related to muscles; therefore, if symptoms such as muscle pain or weakness occur, especially when taking high doses, it is essential to inform a doctor immediately. This drug should not be used by individuals with certain liver diseases or by women who are pregnant or breastfeeding, and caution is required in patients with impaired liver function. Additionally, this drug has a high potential for interactions with other medications, so if you are taking other medications, you must inform your doctor or pharmacist. Elderly patients, those with reduced kidney function, and patients with hypothyroidism require closer monitoring while taking this drug. During the use of this drug, regular liver function tests and muscle-related tests must be conducted, and if abnormal symptoms arise, immediate consultation with healthcare providers is required. Taking this drug with grapefruit juice or certain antibiotics, antifungals, and antiviral medications may increase the risk of side effects. Women planning to become pregnant or who may be pregnant must ensure they are using contraception before taking this drug, and if pregnancy is confirmed, the drug must be discontinued immediately. This drug is limited in use for children and adolescents, particularly not used in children under 10 years old. In case of overdose, go to a medical facility immediately for appropriate treatment, and this drug should be stored out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, difficulty breathing or shortness of breath, asthma attack, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Abdominal pain
• fatigue
• constipation
• diarrhea
• dyspepsia
• bloating
• nausea
• headache
• upper respiratory infection
• atrial fibrillation

This drug may be sensitive to air and moisture, so it should be stored in a tightly closed container. The storage temperature should be maintained at room temperature between 1 degree and 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance

Red brick-colored oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle