Femosone Tablet 1/10 (Estradiol Hemihydrate (Micronized), Dydrogesterone)

Adult dose

1. Initial dosage For the first 28-day cycle, take one tablet of white tablet (estradiol 1 mg) daily for the first 2 weeks, then take one tablet of gray tablet containing estradiol 1 mg and dydrogesterone 10 mg for the next 2 weeks. Start a new 28-day cycle on the 29th day. It is recommended to start dosing on the first day of menstruation, and postmenopausal patients may start treatment at any time.

This medication should not be used by children under 18 years of age or by women who are pregnant or breastfeeding. It should not be administered to patients with or suspected of having breast cancer or tumors responsive to estrogen or progestogens. Patients with abnormal genital bleeding, endometrial hyperplasia, thrombosis, liver disease, cerebrovascular disease, or thrombotic tendencies should also use this medication with caution. Patients with allergies to this medication's components or genetic issues like lactose intolerance should avoid taking it. If symptoms such as liver dysfunction, jaundice, migraines, visual disturbances, or increased blood pressure appear, immediately inform a doctor. For patients with a history of thrombosis or those with limited mobility post-surgery, measures must be taken to reduce the risk of thrombosis. Diabetic patients who require blood sugar control must be closely monitored regarding carbohydrate metabolism. Various adverse reactions like endometrial hyperplasia, breast cancer, thrombosis, liver disease, hypertension, headaches, immune disorders, etc., may occur during treatment, so regular check-ups and consultations with a doctor are necessary. In particular, since the risk of breast cancer may increase, regular breast cancer screening is recommended, and any abnormalities in the breast should be reported immediately. This medication may interact with other drugs, so if you are taking other medications, you must inform your doctor or pharmacist. Antiepileptic drugs, HIV medications, and some herbal preparations may reduce the efficacy of this medication or cause bleeding. Pregnant or breastfeeding women should not use this medication, and if pregnancy is confirmed during treatment, it should be immediately discontinued and a doctor consulted. In case of overdose, symptoms such as nausea, vomiting, dizziness, abdominal pain, and drowsiness may occur; in such cases, notify medical personnel immediately. This medication does not significantly affect driving or operating machinery, but caution is needed as it may vary by individual. Finally, this medication is used for hormone replacement therapy in postmenopausal women, and regular check-ups and monitoring according to the doctor's instructions are important before and during medication.

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, angioedema, cold sweat, pallor, severe allergic reactions, severe rashes accompanied by fever, blisters, peeling skin, mucous membrane pain in mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice)

Mild side effects

Headache, abdominal pain, breast pain, breast tenderness, lower back pain, nausea, vomiting, abdominal bloating, indigestion, migraine, depression, irritability, dizziness, changes in libido, gallbladder disorder, changes in liver function indices, breast enlargement, skin allergic reactions (rash, itching), purpura, vaginal candidiasis, menstrual disorders (postmenopausal bleeding, uterine bleeding or spotting during non-menstrual periods, menorrhagia, oligomenorrhea, amenorrhea, menstrual irregularities, dysmenorrhea), pelvic pain

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain storage temperature between 1 degree and 30 degrees Celsius at room temperature. This will help preserve the medication's effects for a longer period.

Appearance

White tablet: white round, bilaterally convex film-coated tablet Gray tablet: gray round, bilaterally convex film-coated tablet

Package unit

28 tablets/PTP