Clonic Tablet 125 mg (Clonixin Lysine Salt)

Adult dose

Adults: Take 125∼250mg of clonixin lysinate orally 3 times daily.

This medication should be used with caution in individuals who regularly consume more than three alcoholic beverages per day, as it may increase the risk of gastrointestinal bleeding; always consult a physician or pharmacist. Non-steroidal anti-inflammatory drugs (NSAIDs), including this medication, may increase the risk of problems related to the heart and cerebrovascular system, so special care is needed in patients with cardiovascular diseases or risk factors. This medication can cause serious gastrointestinal issues like ulcers, bleeding, or perforation, so extra caution is warranted for individuals with gastrointestinal health issues or the elderly. Patients with a history of peptic ulcers or gastrointestinal problems caused by drugs, those allergic to this medication's components, or those who have had allergic reactions to aspirin should not take this medication. Pregnant women or those who may become pregnant, as well as patients with severe liver, kidney, or heart dysfunction, should not use this medication. While taking this medication, it should not be combined with other NSAIDs, certain antihypertensive drugs, or medications affecting blood coagulation; any existing medications should be discussed with a doctor. Before taking this medication, inform your physician or pharmacist if there is a history of peptic ulcers, hypertension, heart failure, asthma, liver impairment, or kidney dysfunction. Extra caution is also required for children and the elderly. If symptoms such as gastrointestinal bleeding, skin rashes, respiratory distress, severe headache, dizziness, unusual sweating, chills, euphoric feelings, changes in platelet function, or temporary infertility occur during treatment, immediately discontinue use and consult medical personnel. This medication should be taken at the minimum effective dose for the shortest duration possible, and long-term users should undergo regular blood tests and liver and kidney function evaluations. Breastfeeding women should stop nursing or discontinue this medication as it may pass into breast milk. This medication can cause severe skin reactions and allergic responses such as anaphylaxis. If any abnormal skin symptoms appear, discontinue use immediately. Lastly, keep this medication out of reach of children and avoid transferring it to other containers.

• gastrointestinal bleeding
• serious cardiovascular thrombotic events
• myocardial infarction
• stroke
• gastric or intestinal bleeding
• ulcers
• perforation
• nausea
• vomiting
• diarrhea

Drug interactions

Do not take this medication with non-steroidal anti-inflammatory drugs (NSAIDs), ACE inhibitors or angiotensin II receptor antagonists, aspirin, diuretics, lithium, methotrexate, coumarin anticoagulants (such as warfarin), cyclosporine and tacrolimus, antiplatelet agents, or selective serotonin reuptake inhibitors (SSRIs), corticosteroids. Before taking this medication, be sure to inform about concomitant treatment for peptic ulcers, like misoprostol.

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is safe to store it at room temperature between 1°C and 30°C. Therefore, always ensure the lid is tightly closed when storing the medication and avoid extremes of hot or cold temperatures.

Appearance

Pink rectangular film-coated tablet

Package unit

10 tablets (10 tablets/PTP x 1)