Oxyquin Tablet 200 mg (Hydroxychloroquine Sulfate)

Adult dose

1. Rheumatoid arthritis and other conditions: The initial dose is 200~400mg per day; if administering 400mg, divide the dose. Once an effect is seen, reduce the dose to 200mg per day; if the effect is inadequate, increase to 400mg. The maintenance dose should be the minimum effective dose and must not exceed 6.5mg/kg/day. 2. Treatment of malaria: Administer an initial dose of 800mg, followed by 3 additional doses of 400mg at 6~8-hour intervals, for a total of 2g over 2 days. For acute illness, a single dose of 800mg may be administered. 3. Prevention of malaria: Administer 6mg/kg once weekly (usually 400mg once weekly), starting 2 weeks before exposure.

Child dose

1. Rheumatoid arthritis and other conditions: The usual average daily dose is 200~400mg. The maintenance dose should be the minimum effective dose and must not exceed 6.5mg/kg/day. Do not exceed the adult dose, regardless of body weight. 2. Treatment of malaria: Administer an initial dose of chloroquine 10mg/kg, followed by 3 additional doses of 5mg/kg at 6~8-hour intervals, for a total of 25mg/kg over 2 days. Do not exceed the adult dose. 3. Prevention of malaria: Administer 6mg/kg once weekly, starting 2 weeks before exposure. In children weighing 30~40kg or less, even 1 tablet (200mg) may result in an excessive dose, so it is preferable not to administer this medicine.

This medication should not be administered to certain patients. For example, those allergic to this medication or similar compounds, individuals with issues in certain parts of the eye, those taking medications that can cause visual impairment, children, pregnant or nursing women, and people with genetic lactose intolerance should not take this medication. Additionally, caution is required when administering this medication to certain patients. Patients with an allergy to quinine, psoriasis, liver disease, kidney disease, severe gastrointestinal disorders, neurological disorders, blood disorders, or porphyria should use this medication carefully. This medication can cause various side effects. Vision disturbances such as vision blurriness or retinal anomalies, corneal opacities can occur in the eyes, while skin reactions like rashes, hair loss, and in severe cases serious skin reactions such as Stevens-Johnson syndrome may appear. Gastrointestinal symptoms such as nausea, diarrhea, and abdominal pain may occur, as well as central nervous system symptoms like headaches, drowsiness, hallucinations, and psychiatric symptoms may be present. Muscle weakness or blood-related abnormalities, cardiac arrhythmias, liver damage, depression, and mental changes have also been reported. If these symptoms arise, it is essential to consult a physician immediately. Regular eye examinations are required during the duration of medication use, and the medication should be discontinued immediately if any vision abnormalities occur. Patients with poor liver or kidney function should be monitored closely for drug concentration and may need dose adjustments. This medication can interact with other drugs, so patients should inform their healthcare provider of any other ongoing medications. Particularly, concurrent use with drugs that can induce cardiac arrhythmias may be unsafe. Pregnant or nursing women should not use this medication and should discontinue breastfeeding. Additionally, it should be stored out of reach of children, as overdose can lead to serious side effects, and caution is necessary. In case of overdose, immediate gastric lavage and appropriate emergency treatment should be provided, and in severe cases, hospitalization for intensive care may be required.

Visual disturbances, retinal abnormalities, decreased sensitivity of the cornea, corneal opacity, retinopathy, visual impairment, scotoma, halos, glare, skin rash, urticaria, pigmentation changes in the skin and mucosa, hair discoloration, alopecia, vesicular rash, erythema multiforme, mucocutaneous syndrome, photosensitivity reactions, exfoliative dermatitis, Sweet's syndrome, severe cutaneous adverse reactions, acute generalized exanthematous pustulosis, DRESS syndrome, nausea, diarrhea, loss of appetite, abdominal pain, upper abdominal cramps, vomiting, muscle weakness, fatigue, sensorineural hearing loss, hallucinations, headache, drowsiness, restrictive neurobehavioral reactions, mood swings, nightmares, tinnitus, dizziness, hearing loss, unstable emotional changes, psychosis, seizures, skeletal muscle myopathy, neuromuscular disorder, perceptual changes, decreased reflexes, abnormal nerve conduction, aplastic anemia, agranulocytosis, leukopenia, thrombocytopenia, bone marrow suppression, QT prolongation, torsades de pointes, ventricular tachycardia, ventricular tachycardia, cardiomyopathy, left ventricular hypertrophy, conduction disturbances, abnormal liver function test results, fulminant hepatic failure, hepatocellular injury, cholestatic liver injury, acute hepatitis, mixed hepatocellular/cholestatic liver injury, fulminant liver failure, depression, hallucinations, anxiety, agitation, confusion, delusions, mania, sleep disturbances, weight loss, lethargy

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is best kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication over time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle