Metrogel 0.75% (Metronidazole)

Adult dosage

Injection: After cleansing the affected area, apply a thin layer uniformly to the entire affected area twice a day (morning and evening) and rub in.

This medication should not be used by patients who are allergic to any of its ingredients or similar compounds. It is advisable not to administer this drug to breastfeeding women and children. Patients who have taken disulfiram within the last two weeks should also avoid using this medication. Patients with severely impaired liver function may need to exercise caution due to slowed metabolism of this drug. Patients with issues affecting the central nervous system or abnormalities in blood, including bleeding disorders, should use this medication with caution. This drug has the potential to cause various side effects, including skin allergic reactions, gastrointestinal discomfort, and neurological symptoms, so if any symptoms appear, usage should be immediately discontinued, and a doctor should be consulted. It is recommended to avoid sexual intercourse while using this medication, and ensure that the treatment area is not exposed to sunlight or artificial ultraviolet light. Long-term use of this medication may lead to other infections, so it’s essential to use it only for the necessary duration. Alcoholic beverages or medications containing alcohol should be avoided to prevent severe side effects. Patients taking medications that affect blood clotting or lithium should undergo blood tests and dosage adjustments when using this drug. In early pregnancy, there may be effects on the fetus, so women who are pregnant or may become pregnant should use it with caution, and breastfeeding should be avoided. This medication is for external use only, and care should be taken to avoid contact with the eyes; if it does come in contact, rinse thoroughly immediately.

Serious side effects

• Hives → Severe allergic reaction
• Seizures → Severe neurological symptoms
• Peripheral neuropathy (abnormal nerve signs) → Severe neurological symptoms

Mild side effects

Contact dermatitis, erythematous rash, flushing, congestion, dryness of the mouth, skin, vagina, or vulva, fever, itching, pain, joint pain, worsening of symptoms, abdominal discomfort, constipation, coated tongue, glossitis, stomatitis, pancreatitis, abdominal cramps, nausea, vomiting, altered taste, loss of appetite, abdominal bloating, diarrhea, thirst, dry mouth, flattening of T waves on electrocardiogram, reversible neutropenia, thrombocytopenia, vaginal discharge, symptomatic cervicitis.

This medication may be sensitive to air or moisture; therefore, it should be stored in a tightly sealed container. It is advisable to maintain the storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Colorless or pale yellow transparent gel

Package unit

1 tube/box (15g/tube)