Medication info
Grippin-S Tablets (Dexibuprofen)

Grippin-S Tablets (Dexibuprofen)

OTC medicationTablet경구
Ingredient · strength
Dexibuprofen›300mg / 1 tablet
Manufacturer / importer
신일제약(주)
Appearance
Pink round film-coated tablets
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 200202148 · Notified 2002.08.27 · Insurance code 653800060

Summary

Main use
Relief of inflammation and pain in chronic polyarthritis and rheumatoid arthritis
Who takes it
Adults
Adult dose
Administer 300 mg of dexibuprofen orally 2 to 4 times a day. However, do not exceed 1,200 mg of dexibuprofen per day.

Ingredients

Manufacturer
신일제약(주)

Efficacy & effects

Relief of inflammation and pain in chronic polyarthritis and rheumatoid arthritis

  • Chronic polyarthritis
  • rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • painful swelling
  • inflammation
  • pain
  • fever
View approved original text

This medication is used for various joint diseases, including chronic polyarthritis and rheumatoid arthritis. It also helps alleviate pain and inflammation caused by osteoarthritis and ankylosing spondylitis. It is effective in reducing painful swelling and inflammation that can occur after trauma or surgery. Additionally, it assists in the treatment of infections accompanied by inflammation, pain, and fever. Due to these effects, it is used to improve overall inflammatory diseases and pain.

How to take

Adult dose

Administer 300 mg of dexibuprofen orally 2 to 4 times a day. However, do not exceed 1,200 mg of dexibuprofen per day.

Precautions

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than 3 alcoholic drinks per day, so it is essential to consult a doctor or pharmacist before use. This medication may affect the cardiovascular system and increase the risk of serious cardiovascular diseases such as myocardial infarction or stroke. Individuals with underlying cardiovascular diseases or risk factors should exercise increased caution and closely monitor for the occurrence of symptoms with their physician. This medication can cause severe adverse reactions such as gastrointestinal bleeding, ulcers, or perforation, so if gastrointestinal symptoms occur during use, immediate consultation with medical personnel is necessary. Elderly patients or those with a history of gastrointestinal diseases should be particularly cautious. Patients with a history of gastrointestinal ulcers or bleeding, severe blood abnormalities, liver or kidney dysfunction, heart failure, hypertension, and asthma should not use this medication for safety. Combining this medication with aspirin, other non-steroidal anti-inflammatory drugs, or high-dose methotrexate may increase the risk of side effects, so they should not be taken together. During use, breastfeeding should be stopped or consulted with a physician. Dizziness or fatigue may occur, so caution is necessary when driving or operating machinery. Individuals with blood abnormalities, liver/kidney function issues, heart failure, hypertension, history of allergic reactions, elderly patients, and children (over 6 years old) must consult medical personnel before use. If serious adverse symptoms such as shock, blood abnormalities, gastrointestinal symptoms, skin rashes, allergic reactions, liver function abnormalities, respiratory issues, kidney problems, cardiovascular issues, or neurological abnormalities occur during use, discontinue the medication immediately and consult medical personnel. This medication should be used at the minimum effective dose and for the shortest duration necessary, with regular blood tests and liver/kidney function tests required for long-term use. During pregnancy, particularly after the 6th month, this medication may affect the fetus, so it should be avoided or used only after consulting a doctor. In the event of an overdose, even without symptoms, immediate medical treatment is necessary, and the medication should be stored out of the reach of children in a cool place, avoiding direct sunlight and moisture.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, oral/ocular mucosal pain, wheezing or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, lightning-type headaches, seizures, altered consciousness, visual disturbances, paralysis, urination issues

Mild side effects

  • Dyspepsia
  • abdominal distension
  • heartburn
  • epigastric pain
  • diarrhea
  • constipation
  • loss of appetite
  • nausea
  • vomiting
  • abdominal pain
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  • gastrointestinal discomfort
  • thirst
  • stomatitis
  • erythema multiforme
  • hair loss
  • angioedema
  • eczema
  • rash
  • itching
  • purpura
  • rhinitis
  • hypotension
  • hypertension
  • palpitations
  • tinnitus
  • deafness
  • abnormal taste
  • fatigue
  • drowsiness
  • headache
  • dizziness
  • anxiety
  • restlessness
  • confusion
  • depression
  • psychiatric symptoms
  • agitation
  • excitement
  • spatial disorientation

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

Do not take this medication with aspirin, other non-steroidal anti-inflammatory drugs, or high doses of methotrexate. Corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors or angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants (such as warfarin), baclofen, immunosuppressants (such as cyclosporine, tacrolimus, sirolimus),

Storage

This medication should be stored in a sealed container to prevent air exposure, avoiding direct sunlight and keeping it at room temperature. This helps maintain the effectiveness of the medication and prevents degradation.

Appearance and packaging

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.