Prastan Tablets 10 mg (Pravastatin Sodium)

Adult dose

Before starting treatment, patients should begin a low-cholesterol diet, which should be continued throughout the treatment. The usual starting dose is a single dose of 10mg, 20mg, or 40mg once daily. The dosage can be increased to a maximum of 40mg depending on the patient's response. The maintenance dose is 10-40mg once daily. For patients with a history of myocardial infarction or unstable angina, the treatment goal is achieved with 40mg/day of Pravastatin Sodium.

This medication should not be used in certain patients. For example, individuals who are allergic to this drug or have liver function issues should not take it. Women who are pregnant or breastfeeding, children, and those with severe liver or kidney dysfunction should also be cautious with this medication. Additionally, those with muscular diseases or issues affecting bile flow should avoid taking this drug. This medication contains lactose, so individuals with lactose intolerance or related genetic disorders must not use it. Individuals with a history of severe liver disease or kidney disease should use this medication with caution, and attention is also required for those taking other medications that may interact with it. Particularly, those consuming large amounts of alcohol or suffering from muscular weakness should exercise special caution when using this medication. During treatment with this drug, skin rash or allergic reactions may occur, so if such symptoms arise, it is crucial to immediately discontinue use and consult a doctor. Gastrointestinal symptoms such as diarrhea, nausea, vomiting, and signs of liver dysfunction may be observed, hence regular check-ups are necessary. Muscle pain or weakness, and in severe cases, renal function deterioration due to muscle breakdown can occur, so any muscle-related symptoms should be promptly reported to healthcare professionals. Central nervous system symptoms such as headaches, dizziness, and depression have been reported infrequently, and cognitive impairment such as memory loss may occur. This medication inhibits cholesterol synthesis, reducing cholesterol levels in the blood; however, it may potentially affect adrenal or gonadal hormones. Therefore, caution is required if there are abnormalities in endocrine functions. Before treatment, it is important to confirm a definitive diagnosis of hypercholesterolemia and to implement non-drug treatments like dietary and exercise therapy first. During treatment, blood lipid levels should be regularly monitored to evaluate treatment effectiveness, and if no effect is observed, the medication should be discontinued. If there are signs of myositis or muscle damage, it is recommended to discontinue use immediately, especially for older adults over 65, patients with hypothyroidism, or those with impaired kidney function. This medication may increase the risk of muscle damage when taken with other lipid-lowering agents or specific immunosuppressants, so strict adherence to medical instructions is necessary when in combination therapy. Women who are pregnant or may become pregnant should not take this medication, and if pregnancy is confirmed, it should be discontinued immediately. Women who are breastfeeding are also advised against using this medication. The safety and efficacy in children under 18 have not been established, so it should not be used in this age group. Elderly individuals may have decreased physical function, so caution should be exercised in adjusting the dosage. In case of overdose, immediate medical attention is necessary for tests including liver function. It is more effective to take this medication after dinner, and timing should be properly maintained if taken with other medications that require intervals. Finally, this medication should be kept out of reach of children, and changing containers is not advised, as it is important for quality maintenance.

Serious side effects

Hives, severe swelling (including angioedema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough + fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, loss of consciousness.

Mild side effects

• Rash
• pruritus
• diarrhea
• nausea
• vomiting
• constipation
• abdominal pain
• upper gastrointestinal discomfort
• stomatitis
• heartburn

This medication should be stored in a sealed container to avoid exposure to air or moisture, and it is safe to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

White round tablets.

Package unit

30 tablets/bottle, 100 tablets/bottle