Dongsung Simvastatin Tablets

Adult dose

Administer once daily in the evening. The initial starting dose is 40 mg, with patients with hyperlipidemia generally starting at 20 mg. Patients with mild to moderate hypercholesterolemia may start with 10 mg. The dosage can be adjusted within the range of 5 to 40 mg once daily in the evening. Dosage adjustments are required for specific patient groups and in combination therapy (e.g., elderly patients may start at 20 mg, while for those taking verapamil or diltiazem, appropriate adjustments are needed).

Child dose

For pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia, the recommended initial dose is 10 mg once daily, with a recommended dosage range of 10 to 40 mg. The maximum dose is 40 mg daily.

This medication is designed to lower blood cholesterol levels and help reduce the risk of cardiovascular diseases. When taking this medication, muscle pain or weakness may occur, and if such symptoms arise, you should immediately inform your doctor. Caution is particularly required when taking a high dosage (80 mg), as the risk of muscle-related side effects increases. Because it may affect liver function, patients with liver disease or abnormal liver function test results should not take this medication or must follow their doctor's instructions. Pregnant or potentially pregnant women, as well as breastfeeding women, should not take this medication. This medication may increase the risk of side effects when taken with certain antibiotics, antifungals, and some cardiac drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist. Patients who consume excessive alcohol or have liver or kidney function issues must be more cautious while taking this medication. Elderly individuals and women may experience muscle side effects more frequently and should be careful when taking this medication. It is advisable to regularly check liver function and muscle enzyme levels through blood tests while taking this medication. If any unexplained muscle pain, tenderness, or weakness occurs while taking the medication, you should consult your healthcare provider immediately. This medication contains lactose, so patients with lactose intolerance should not take it. Additionally, this medication may raise blood sugar levels in some patients, so patients at risk of diabetes should periodically check their blood sugar levels. When taking this medication, it is best to avoid certain foods like grapefruit juice, and if a new medication is prescribed during the course of treatment, you must inform the prescriber about this medication. Children, especially those under 10 years of age or pre-menarchal, should not be administered this medication. Finally, store this medication out of reach of children and keep it in its original container.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

Abdominal pain, weakness, constipation, diarrhea, indigestion, bloating, nausea, headache, upper respiratory infection, atrial fibrillation, gastritis, diabetes, myalgia, insomnia, dizziness, bronchitis, sinusitis, eczema, urinary tract infection, alopecia, itching, skin changes, flat atrophy-like drug rash, gynecomastia, decreased libido, sexual dysfunction (including erectile dysfunction), progression of cataracts, ocular muscle paralysis, anemia, thyroid dysfunction, transient and mild liver function test abnormalities

This medication should be stored in a tightly sealed container to prevent air ingress and kept at a temperature between 1 to 30 degrees Celsius in a room. Storing it this way will help maintain its effectiveness.

Appearance

Brownish-yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle