Collesnon 20 mg (Simvastatin)

Adult dose

This medication is taken once daily in the evening. The initial starting dose is 20 mg once daily; for patients with mild to moderate hypercholesterolemia, it can start at 10 mg. The dosage can be adjusted within the range of 5 - 40 mg per day based on the initial LDL cholesterol level, treatment goals, and patient response. Certain patient groups have dosage restrictions; for example, in combination with verapamil, diltiazem, or dronedarone

Child dose

For pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia, the recommended starting dose is 10 mg once daily in the evening. The recommended dosage range is 10 - 40 mg per day, with a maximum dose of

This medication is primarily used to lower cholesterol levels in the blood to prevent cardiovascular diseases. When taking this medication, there is a risk of muscle-related problems; therefore, if symptoms such as muscle pain or weakness occur, you must inform your doctor immediately. Particularly, there is an increased risk of serious muscle injury such as myopathy or rhabdomyolysis when taken at high doses, so caution is necessary. Patients with hypersensitivity to this medication or those with liver disease, pregnant women or women who may become pregnant, and breastfeeding women should not take this medication. Moreover, the risk of muscle damage may increase when used in combination with certain medications, so if you are taking other medications, you must inform your doctor or pharmacist. Regular liver function tests are necessary for patients with a history of liver disease or suspected liver dysfunction, as this medication can affect liver function. Older adults, patients with impaired renal function, and those with hypothyroidism need to be monitored more closely when taking this medication. Pregnant women should not take this medication, and women planning to become pregnant should consult a doctor before taking it. During breastfeeding, this medication should be avoided, and if necessary, breastfeeding should be discontinued. This medication is only to be used in children aged 10 years and older, particularly patients with familial hypercholesterolemia aged 10-17 years; other children are advised against taking it. Certain food items such as grapefruit juice should be limited during treatment, and in case of overdose, an immediate visit to a healthcare facility is required. To use this medication safely, regular blood tests and adherence to the doctor's instructions are very important.

Serious side effects

Myopathy, rhabdomyolysis, severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweats, pallor), severe skin reactions (rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa), respiratory problems (shortness of breath or difficult breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever), liver abnormalities and jaundice (yellowing of the skin or eyes, extreme fatigue)

Mild side effects

• Abdominal pain
• weakness
• constipation
• diarrhea
• indigestion
• bloating
• nausea
• headache
• upper respiratory infection
• atrial fibrillation

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, and it is safe to store at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

Yellowish oval film-coated tablet with a reddish tint

Package unit

30 tablets/bottle, 300 tablets/bottle