Medication info
Zacitin 0.25 mg (Alprazolam)

Zacitin 0.25 mg (Alprazolam)

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.25mg / 1 tablet
Manufacturer / importer
Medica Korea Co., Ltd.
Appearance
White oval tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200109957 · Approved 1989.08.01 · Insurance code 646002040

Summary

Main use
Relief of symptoms of anxiety disorders and anxiety (including with coexisting depression), panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
Individualize the dose to achieve maximum benefit. The usual daily doses listed below are appropriate for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse reactions. The risk of dependence may increase with dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest duration possible and frequently reassess the need for continued treatment. 1. The initial dose of alprazolam is 0.25-0.5㎎ 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ 2-3 times daily. Reduce the dose if adverse reactions occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this drug orally in 3 divided doses. If increasing the dose, increase gradually to a maximum of 2.4㎎ per day, administered orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder The initial dose of this drug is 0.5㎎. Depending on the patient's response to treatment, increase by no more than 1㎎ at intervals of 3-4 days to a daily average of 5-6㎎, divided into 3-4 doses. To discontinue treatment, reduce the dose by no more than 0.5㎎ every 3 days; a lower dose reduction may be required in some cases.

Ingredients

Manufacturer
Medica Korea Co., Ltd.

Efficacy & effects

Relief of symptoms of anxiety disorders and anxiety (including with coexisting depression), panic disorder, and psychosomatic disorders

  • Anxiety disorders
  • anxiety symptoms
  • anxiety accompanying depression
  • anxiety in psychosomatic disorders
  • tension
  • depression
  • sleep disorders
  • panic disorders
View approved original text

This medicine is used for the treatment of anxiety disorders and the short-term alleviation of anxiety symptoms, also effective for anxiety symptoms accompanying depression. It also helps improve anxiety, tension, depression, and sleep disorders appearing in psychosomatic disorders such as gastric or duodenal ulcers, irritable bowel syndrome, and autonomic dysfunction. It is also used to treat panic disorders by alleviating symptoms. In short, this medication is used for anxiety disorders, anxiety related to depression, symptoms related to psychosomatic disorders, and panic disorders.

How to take

Adult dose

Individualize the dose to achieve maximum benefit. The usual daily doses listed below are appropriate for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse reactions. The risk of dependence may increase with dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest duration possible and frequently reassess the need for continued treatment. 1. The initial dose of alprazolam is 0.25-0.5㎎ 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ 2-3 times daily. Reduce the dose if adverse reactions occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this drug orally in 3 divided doses. If increasing the dose, increase gradually to a maximum of 2.4㎎ per day, administered orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder The initial dose of this drug is 0.5㎎. Depending on the patient's response to treatment, increase by no more than 1㎎ at intervals of 3-4 days to a daily average of 5-6㎎, divided into 3-4 doses. To discontinue treatment, reduce the dose by no more than 0.5㎎ every 3 days; a lower dose reduction may be required in some cases.

Precautions

This drug is a benzodiazepine that acts on the central nervous system and is used for sedation and anxiety relief. Caution should be taken when taking this drug with narcotics, as it can lead to severe sedation effects, respiratory depression, coma, and, in severe cases, death. Due to the risk of misuse and dependence, this medication should only be used in appropriate doses and for the duration prescribed by a physician, and unused medication should be properly stored and disposed of. This drug should not be administered to patients with hypersensitivity or specific diseases (acute closed-angle glaucoma, severe myasthenia gravis, severe respiratory failure, severe liver failure, etc.). Patients with heart, liver, or kidney problems, as well as the elderly and frail patients, should use this drug with caution due to the higher risk of side effects. This drug can cause drowsiness, dizziness, and decreased concentration, so driving or operating hazardous machinery should be avoided. During long-term use, regular blood tests and liver function tests should be conducted, and sudden discontinuation may cause withdrawal symptoms and seizures, so dosage should be reduced gradually. This drug should be administered cautiously to patients with depression, psychotic symptoms, and suicidal risks, and if abnormal behaviors or mood changes occur, a doctor should be consulted immediately. The effectiveness may be enhanced or the risk of side effects increased when combined with other central nervous system depressants, alcohol, certain antibiotics, antidepressants, etc., so it is essential to inform the physician of all medications being taken. During late pregnancy, it may pose risks to the fetus and newborn, so it should not be administered, and if breastfeeding, administration should be avoided or breastfeeding should be discontinued. In case of overdose, severe drowsiness, respiratory depression, and coma may occur, requiring immediate emergency care. This drug should be kept out of reach of children for safety and stored in its original container to prevent quality degradation and misuse.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle cramps
  • vomiting
  • sweating
  • tremors
  • convulsions
  • excitement
  • increased muscle rigidity
  • sleep disturbances
Show 164 more
  • hallucinations
  • anxiety
  • anger
  • irritability
  • aggressive behavior
  • hostile behavior
  • hypersensitivity
  • hostility
  • obsessive thoughts
  • drowsiness
  • headache
  • depression
  • confusion
  • disorientation
  • decreased libido
  • anxiety
  • nervousness
  • increased libido
  • mania
  • hallucinations
  • anger
  • anxiety
  • drug dependence
  • hypomania
  • aggression
  • hostility
  • abnormal thoughts
  • processive movements
  • drug abuse
  • memory impairment
  • speech disturbances
  • dizziness
  • balance disorders
  • coordination disorders
  • attention deficit
  • hypersomnia
  • somnolence
  • tremors
  • amnesia
  • autonomic nervous system imbalance
  • abnormal muscle tension
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • gastrointestinal disturbances
  • hepatitis
  • abnormal liver function
  • jaundice
  • dermatitis
  • angioedema
  • photosensitivity reactions
  • muscle weakness
  • urinary incontinence
  • urinary retention
  • sexual dysfunction
  • menstrual irregularities
  • fatigue
  • irritability
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • increased intraocular pressure
  • drowsiness
  • mild headache
  • depression
  • headache
  • confusion
  • insomnia
  • nervousness
  • fainting
  • dizziness
  • inability to sit still
  • thirst
  • diarrhea
  • increased salivation
  • tachycardia
  • palpitations
  • hypotension
  • excitement
  • tremors
  • dermatitis
  • allergy
  • nasal congestion
  • weight gain
  • weight loss
  • fatigue
  • coordination disorders
  • memory damage
  • involuntary movement disorders
  • decreased libido
  • confusional state
  • muscle single contraction
  • abnormal muscle tone
  • fainting
  • inability to sit still
  • anxiety
  • disinhibition
  • sensory disturbances
  • polyuria
  • vascular motor disturbances
  • unreality
  • abnormal dreams
  • fear
  • warm sensation
  • decreased salivation
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory infection
  • tinnitus
  • muscle cramps
  • muscle rigidity
  • sweating
  • rash
  • increased appetite
  • decreased appetite
  • urination disorders
  • menstrual disorders
  • erectile dysfunction
  • edema
  • urinary incontinence
  • infection
  • seizures
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • elevated liver enzymes
  • jaundice
  • delirium
  • apathy
  • hyperactivity
  • dyspepsia
  • asthenia
  • chest pain
  • malaise
  • falling
  • ataxia
  • excessive sedation
  • unclear speech
  • jaundice
  • itching
  • double vision
  • changes in libido
  • urinary incontinence
  • urinary retention
  • seizures
  • hallucinations
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • elevated liver enzymes
  • jaundice
  • Stevens-Johnson syndrome
  • gynecomastia
  • galactorrhea
  • drowsiness
  • ataxia
  • unclear language
  • coma
  • respiratory depression

Not everyone experiences these, and they can vary from person to person.

Storage

This medicine may be sensitive to light, so it should be stored in a tightly sealed container that blocks light. It is also important to keep the medicine at room temperature, avoiding overly hot or cold environments.

Appearance and packaging

Appearance

White oval tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.